DENND4A and SERTAD1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		DENND4A	SERTAD1
Gene Name		DENN/MADD domain containing 4A	SERTA domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	DNA Binding Rab Guanyl-nucleotide Exchange Factor Activity	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Rab GTPase Activity	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription, DNA-templated Positive Regulation Of Cell Proliferation Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978) Red blood cell traits ( 23222517)
Protein-Protein Interactions		5 interactors: CEBPE PCBD1 SERTAD1 TLX3 YWHAG	36 interactors: ASB8 ATXN7L3 CCND2 CDK4 CDKN2A CHURC1 CIB3 COPB1 CREBBP DENND4A EGLN3 EP300 FAH HIVEP1 HSPB1 KAT2B KLHL42 MVP P4HA3 PATE1 POT1 PRDM4 RBX1 RCHY1 ROPN1 SETD7 SFI1 SMAD3 SPEN STAT5B SUPT7L TCEB1 TGM2 TLR4 TRIM28 ZNF410
Entrez ID		10260	29950
HPRD ID		02662	15326
Ensembl ID		ENSG00000174485
Uniprot IDs		Q05C90 Q7Z401	Q53GC0 Q9UHV2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Tetrahydrobiopterin Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression L-phenylalanine Catabolic Process Positive Regulation Of Cellular Biosynthetic Process L-phenylalanine Metabolic Process Regulation Of Respiratory Gaseous Exchange By Neurological System Process Regulation Of Metabolic Process Regulation Of Respiratory System Process Regulation Of Protein Homodimerization Activity Macrophage Differentiation Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Neuron Differentiation Cytokine Biosynthetic Process Regulation Of Respiratory Gaseous Exchange Regulation Of RNA Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cytokine Metabolic Process Neuron Fate Specification Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Pteridine-containing Compound Biosynthetic Process Regulation Of Neurogenesis RNA Biosynthetic Process Regulation Of Protein Kinase Activity Aromatic Amino Acid Family Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Cellular Metabolic Process Respiratory Gaseous Exchange Regulation Of Cell Development Positive Regulation Of Mitochondrion Organization Pteridine-containing Compound Metabolic Process	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process N-terminal Peptidyl-lysine Acetylation Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Gene Expression Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Peptidyl-lysine Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Response To Hypoxia Cellular Macromolecule Biosynthetic Process RNA Metabolic Process Cellular Protein Modification Process Macromolecule Biosynthetic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Oxygen Levels N-terminal Protein Amino Acid Acetylation Viral Process Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Notch Signaling Pathway Negative Regulation Of Cellular Metabolic Process Cellular Protein Metabolic Process Peptidyl-amino Acid Modification Protein Metabolic Process Chromatin Organization Chromosome Organization Positive Regulation Of Interleukin-1 Production N-terminal Protein Amino Acid Modification Positive Regulation Of Cytokine Production Response To Abiotic Stimulus
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