DCAF7 and AIFM1

		DCAF7	AIFM1
Description		DDB1 and CUL4 associated factor 7	apoptosis inducing factor mitochondria associated 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Body Protein-containing Complex Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	DNA Binding NADH Dehydrogenase Activity Protein Binding NAD(P)H Oxidase H2O2-forming Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H Protein Dimerization Activity FAD Binding Poly-ADP-D-ribose Binding
	Biological Process	Protein Ubiquitination	Response To Ischemia Apoptotic Process Response To Toxic Substance Neuron Differentiation Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Neuron Apoptotic Process Protein Import Into Mitochondrial Intermembrane Space Positive Regulation Of Necroptotic Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hydrogen Peroxide Cellular Response To Estradiol Stimulus Cellular Response To Hypoxia Cellular Response To Nitric Oxide Mitochondrial Disulfide Relay System Response To L-glutamate Cellular Response To Aldosterone
Pathways		Association of TriC/CCT with target proteins during biosynthesis Neddylation
Drugs			Flavin adenine dinucleotide MCC
Diseases			Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Hip circumference adjusted for BMI ( 34021172)	Bipolar disorder ( 31043756)
Interacting Genes		7 interacting genes: APP ATP13A2 BMPR1B DYRK1B LIG1 PWP2 YWHAG	11 interacting genes: CASP3 EIF3G HSPA1A HSPA1B MLH1 NOA1 SETDB1 STC2 TSC22D4 WWC1 XIAP
Entrez ID		10238	9131
HPRD ID		09340	02161
Ensembl ID		ENSG00000136485	ENSG00000156709
Uniprot IDs		P61962	E9PMA0 O95831
PDB IDs			1M6I 4BUR 4BV6 4FDC 4LII 5FMH 5FS6 5FS7 5FS8 5FS9 5KVH 5KVI 8D3E 8D3G 8D3H 8D3I 8D3J 8D3K 8D3N 8D3O 8VGY
Enriched GO Terms of Interacting Partners?		Cellular Response To Manganese Ion Response To Manganese Ion Cellular Response To Stress	Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression C3HC4-type RING Finger Domain Binding ATP-dependent Protein Disaggregase Activity Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Cellular Heat Acclimation Negative Regulation Of Metabolic Process Negative Regulation Of Growth Positive Regulation Of Microtubule Nucleation Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Inclusion Body Assembly Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Inclusion Body Perinuclear Region Of Cytoplasm Regulation Of Microtubule Nucleation Response To Oxidative Stress MRNA Catabolic Process Regulation Of Inclusion Body Assembly Regulation Of Mitotic Spindle Assembly Response To Lipid Execution Phase Of Apoptosis Enzyme Binding Protein Refolding Positive Regulation Of Defense Response Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Erythrocyte Differentiation Aggresome Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand ATP-dependent Protein Folding Chaperone Positive Regulation Of Microtubule Polymerization Regulation Of Spindle Assembly Regulation Of Protein Ubiquitination RNA Catabolic Process Cellular Response To Stress Regulation Of Mitotic Spindle Organization Response To Steroid Hormone Macromolecule Catabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Erythrocyte Differentiation Regulation Of Post-translational Protein Modification Cellular Response To Heat Regulation Of Growth Intracellular Signal Transduction Response To Hormone Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?