TXNDC9 and KLF11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TXNDC9	KLF11
Description		thioredoxin domain containing 9	KLF transcription factor 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Midbody	Chromatin Nucleus Nucleoplasm Cytosol Focal Adhesion Nuclear Body
	Molecular Function	Protein Binding Cadherin Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Microtubule Cytoskeleton Organization	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Apoptotic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Cellular Response To Endothelin Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases			Maturity onset diabetes of the young (MODY)
GWAS		Bipolar disorder ( 21926972) Heel bone mineral density ( 30598549)	Dental caries (decayed, missing and filled teeth) ( 31533690) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Feeling worry ( 29500382) Heel bone mineral density ( 30598549) Height ( 28552196) Mean spheric corpuscular volume ( 32888494) Neurociticism ( 29500382) Prostate cancer ( 23535732)
Interacting Genes		27 interacting genes: C1orf94 C3orf62 CCDC172 CEP126 CEP76 CHD3 COG4 DYDC1 ELP1 EXOSC8 FEZ1 GIT1 IMMT KLF11 LZTS1 MAGEA6 MED22 MRPL12 MYOG PBX4 PICK1 PNMA1 PTN SETDB1 TEX9 TRIM27 ZNF655	13 interacting genes: APH1A APPBP2 ATXN1 CBX1 CBX3 CLU HDAC1 MAPK1 NFYC SIN3A TIMM13 TXNDC9 YWHAZ
Entrez ID		10190	8462
HPRD ID		15592	04488
Ensembl ID		ENSG00000115514	ENSG00000172059
Uniprot IDs		O14530	B7ZAX4 O14901 Q53QU8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Autophagy	Negative Regulation Of Gene Expression, Epigenetic Heterochromatin Formation Heterochromatin Chromatin Binding Epigenetic Regulation Of Gene Expression Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone Methyltransferase Binding Sin3-type Complex Regulation Of RNA Metabolic Process Enzyme Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of Stem Cell Population Maintenance Negative Regulation Of RNA Biosynthetic Process Pericentric Heterochromatin Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Protein Targeting Perinuclear Endoplasmic Reticulum Lumen Nucleus Regulation Of Neuronal Signal Transduction Protein Sequestering Activity Transcription Regulator Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Stem Cell Population Maintenance Nucleoplasm Histone Deacetylase Complex Spindle Negative Regulation Of Protein Localization To Nucleus Site Of DNA Damage Cellular Response To Tert-butyl Hydroperoxide Response To Methylglyoxal Chromatin ERK1 And ERK2 Cascade Rhythmic Process Positive Regulation Of Gliogenesis Transcription Repressor Complex Chromatin Remodeling Negative Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Positive Regulation Of Neurofibrillary Tangle Assembly Krueppel-associated Box Domain Binding Cytosine Metabolic Process Synaptic Target Recognition Negative Regulation Of Activation Of Membrane Attack Complex Negative Regulation Of Metabolic Process Protein-containing Complex Regulation Of Gene Expression Central Nervous System Myelin Maintenance
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