AASS and CHCHD3

		AASS	CHCHD3
Description		aminoadipate-semialdehyde synthase	coiled-coil-helix-coiled-coil-helix domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	SAM Complex Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Crista Junction MICOS Complex Extracellular Exosome MIB Complex
	Molecular Function	Transcription Corepressor Activity Catalytic Activity Saccharopine Dehydrogenase Activity Saccharopine Dehydrogenase (NAD+, L-lysine-forming) Activity Oxidoreductase Activity Histone Binding Saccharopine Dehydrogenase (NADP+, L-lysine-forming) Activity Saccharopine Dehydrogenase (NAD+, L-glutamate-forming) Activity	Protein Binding Phosphatase Binding Molecular Adaptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Lysine Catabolic Process L-lysine Catabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine	Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation
Pathways		Lysine catabolism	Mitochondrial protein import Cristae formation
Drugs		Glutamic acid NADH NADPH L-Saccharopine
Diseases		Hyperlysinemia
GWAS		Opioid dependence (time to event) ( 34124712)	Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)
Interacting Genes		2 interacting genes: OGT WEE2-AS1	40 interacting genes: AMOTL2 ANKS1A ARMC7 BLZF1 CALCOCO2 CATSPERT CBY2 CCDC33 CCDC85B CEP72 CLPP CYSRT1 EFHC1 ENKD1 FANCL GMCL2 GOLGA2 KANK2 KRT40 KRTAP4-12 LMO1 LZTS2 NBPF19 NOTCH2NLA NTAQ1 NUDT3 NUTF2 NUTM1 PDE4DIP PPP1CB RAB3IP RBM11 RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 UBC USHBP1
Entrez ID		10157	54927
HPRD ID		05489	13044
Ensembl ID		ENSG00000008311	ENSG00000106554
Uniprot IDs		A0A7P0T9N4 A4D0W4 Q9UDR5	A4D1N4 B7Z1X9 C9JRZ6 Q9NX63
PDB IDs		5L76 5L78 5O1N 5O1O 5O1P 8DDA 8E8T 8E8U 8E8V
Enriched GO Terms of Interacting Partners?			Spindle Organization Cytoplasm Microtubule Organizing Center Organization Cytoskeleton Centrosome Microtubule Cytoskeleton Organization Microtubule-based Process Centrosome Cycle
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