AASS

Description		aminoadipate-semialdehyde synthase
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Transcription Corepressor Activity Catalytic Activity Saccharopine Dehydrogenase Activity Saccharopine Dehydrogenase (NAD+, L-lysine-forming) Activity Oxidoreductase Activity Histone Binding Saccharopine Dehydrogenase (NADP+, L-lysine-forming) Activity Saccharopine Dehydrogenase (NAD+, L-glutamate-forming) Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Lysine Catabolic Process L-lysine Catabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine
Pathways		Lysine catabolism
Drugs		Glutamic acid NADH NADPH L-Saccharopine
Diseases		Hyperlysinemia
GWAS		Opioid dependence (time to event) ( 34124712)
Novel Interacting Genes		6 novel interacting genes: ARF5 CCR6 CHCHD3 FSCN3 PTPRZ1 WASL
Interacting Genes		2 interacting genes: OGT WEE2-AS1
Entrez ID		10157
HPRD ID		05489
Ensembl ID		ENSG00000008311
Uniprot IDs		A0A7P0T9N4 A4D0W4 Q9UDR5
PDB IDs		5L76 5L78 5O1N 5O1O 5O1P 8DDA 8E8T 8E8U 8E8V
Enriched GO Terms of Interacting Partners?
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