SUGP2 and MIR92A1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		SUGP2	MIR92A1
Description		SURP and G-patch domain containing 2	microRNA 92a-1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Extracellular Space Cytoplasm RISC Complex Extracellular Vesicle
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	RNA Processing MRNA Processing RNA Splicing	Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Acute Inflammatory Response Regulation Of Heart Contraction Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Angiogenesis Positive Regulation Of Interleukin-6 Production Negative Regulation Of Collagen Biosynthetic Process Negative Regulation Of Smooth Muscle Cell Apoptotic Process MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Positive Regulation Of Apoptotic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade Negative Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Positive Regulation Of Programmed Necrotic Cell Death Cellular Response To Fatty Acid Cellular Response To Low-density Lipoprotein Particle Stimulus Positive Regulation Of Monocyte Chemotactic Protein-1 Production Cellular Stress Response To Acid Chemical Vascular Endothelial Cell Response To Fluid Shear Stress Blood Vessel Diameter Maintenance Negative Regulation Of Sprouting Angiogenesis Positive Regulation Of Sprouting Angiogenesis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Negative Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Positive Regulation Of Endothelial Cell Activation Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell
Pathways
Drugs
Diseases
GWAS
Interacting Genes		61 interacting genes: ATXN1 ATXN1L CEBPA EXOSC8 GOLGA2 GSK3A LZTR1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR128-2 MIR138-2 MIR141 MIR143 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR19A MIR19B1 MIR19B2 MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR34B MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-3 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PTEN RNF10	76 interacting genes: ADARB1 C1QBP CELF1 CPSF1 CPSF2 CPSF6 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LRPPRC MATR3 MSI2 NOL6 NONO NUDT21 P3H1 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 QARS1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 WWP2 YBX1 YBX3
Entrez ID		10147	407048
HPRD ID		10469
Ensembl ID		ENSG00000064607	ENSG00000283705
Uniprot IDs		A8K5G0 M0R2Z9 Q8IX01
PDB IDs		1X4P
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Extracellular Vesicle MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Cell Migration Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Developmental Process Regulation Of Translation Negative Regulation Of Signal Transduction Regulation Of Angiogenesis Extracellular Space Regulation Of Vasculature Development Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of MRNA Stability Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of RNA Stability Negative Regulation Of Protein Metabolic Process Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Multicellular Organismal Development	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of RNA Splicing Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Nucleoplasm Ribonucleoprotein Complex MRNA Splicing, Via Spliceosome Nucleus RNA Splicing, Via Transesterification Reactions Spliceosomal Complex Negative Regulation Of MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Catalytic Step 2 Spliceosome Aminoacyl-tRNA Synthetase Multienzyme Complex Cytoplasmic Stress Granule MRNA 3'-UTR Binding Regulation Of Translation Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization MRNA Stabilization Negative Regulation Of Translation Regulation Of MRNA Stability MRNA Cleavage And Polyadenylation Specificity Factor Complex Regulation Of Primary Metabolic Process Regulation Of RNA Stability Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Paraspeckles Negative Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation CRD-mediated MRNA Stabilization Regulation Of Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA 5'-UTR Binding RNA Transport Positive Regulation Of Gene Expression
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