SUGP2 and MIR143

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		SUGP2	MIR143
Description		SURP and G-patch domain containing 2	microRNA 143
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Extracellular Space RISC Complex Extracellular Exosome
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	RNA Processing MRNA Processing RNA Splicing	Regulation Of Smooth Muscle Contraction Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization MiRNA-mediated Post-transcriptional Gene Silencing Angiotensin-activated Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching Positive Regulation Of Angiogenesis Negative Regulation Of D-glucose Import Negative Regulation Of Smooth Muscle Cell Proliferation Aorta Smooth Muscle Tissue Morphogenesis Regulation Of Phenotypic Switching Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Pulmonary Blood Vessel Remodeling
Pathways
Drugs
Diseases
GWAS
Interacting Genes		61 interacting genes: ATXN1 ATXN1L CEBPA EXOSC8 GOLGA2 GSK3A LZTR1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR128-2 MIR138-2 MIR141 MIR143 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR19A MIR19B1 MIR19B2 MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR34B MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-3 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PTEN RNF10	79 interacting genes: ADARB1 APOBEC3B C1QBP CDC5L CELF1 CPSF1 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SART3 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TRA2A TRA2B TUT4 U2SURP UPF1 UTP20 YBX1 YBX3 ZC3H10
Entrez ID		10147	406935
HPRD ID		10469
Ensembl ID		ENSG00000064607	ENSG00000284182
Uniprot IDs		A8K5G0 M0R2Z9 Q8IX01
PDB IDs		1X4P
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Extracellular Vesicle MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Cell Migration Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Developmental Process Regulation Of Translation Negative Regulation Of Signal Transduction Regulation Of Angiogenesis Extracellular Space Regulation Of Vasculature Development Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of MRNA Stability Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of RNA Stability Negative Regulation Of Protein Metabolic Process Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Multicellular Organismal Development	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Macromolecule Metabolic Process Post-transcriptional Regulation Of Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleus Nucleoplasm Ribonucleoprotein Complex Catalytic Step 2 Spliceosome Spliceosomal Complex MiRNA Binding Regulation Of Gene Expression Regulation Of MRNA Processing Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Translation MRNA 3'-UTR Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Cytoplasmic Stress Granule Regulation Of RNA Stability Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation Regulation Of MRNA Stability Negative Regulation Of RNA Catabolic Process Negative Regulation Of Metabolic Process Positive Regulation Of Gene Expression Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process MRNA Stabilization Negative Regulation Of Gene Expression Nucleolus Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome
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