MIR92A1 and CRTAP

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR92A1	CRTAP
Description		microRNA 92a-1	cartilage associated protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm RISC Complex Extracellular Vesicle	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Protein-containing Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Protein Binding Collagen Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Acute Inflammatory Response Regulation Of Heart Contraction Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Angiogenesis Positive Regulation Of Interleukin-6 Production Negative Regulation Of Collagen Biosynthetic Process Negative Regulation Of Smooth Muscle Cell Apoptotic Process MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Positive Regulation Of Apoptotic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade Negative Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Positive Regulation Of Programmed Necrotic Cell Death Cellular Response To Fatty Acid Cellular Response To Low-density Lipoprotein Particle Stimulus Positive Regulation Of Monocyte Chemotactic Protein-1 Production Cellular Stress Response To Acid Chemical Vascular Endothelial Cell Response To Fluid Shear Stress Blood Vessel Diameter Maintenance Negative Regulation Of Sprouting Angiogenesis Positive Regulation Of Sprouting Angiogenesis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Negative Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Positive Regulation Of Endothelial Cell Activation Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell	Protein Folding Spermatogenesis Collagen Fibril Organization Protein Stabilization Negative Regulation Of Post-translational Protein Modification
Pathways			Collagen biosynthesis and modifying enzymes
Drugs
Diseases			Osteogenesis imperfecta
GWAS			Asthma ( 31619474 31959851) Femur bone mineral density x serum urate levels interaction ( 34046847) Major depressive disorder ( 29317602) Multiple sclerosis ( 31604244) Refractive error ( 32231278) Retinal detachment or retinal break ( 31816047)
Interacting Genes		76 interacting genes: ADARB1 C1QBP CELF1 CPSF1 CPSF2 CPSF6 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LRPPRC MATR3 MSI2 NOL6 NONO NUDT21 P3H1 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 QARS1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 WWP2 YBX1 YBX3	26 interacting genes: MIR1-1 MIR10B MIR128-1 MIR138-2 MIR140 MIR16-1 MIR16-2 MIR17 MIR18A MIR199A2 MIR19A MIR19B1 MIR200B MIR200C MIR20A MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIRLET7B MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I OGT RIPPLY3
Entrez ID		407048	10491
HPRD ID			16110
Ensembl ID		ENSG00000283705	ENSG00000170275
Uniprot IDs			C9JP16 O75718
PDB IDs			8K0E 8K0F 8K0I 8K0M 8K17 8KC9
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of RNA Splicing Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Nucleoplasm Ribonucleoprotein Complex MRNA Splicing, Via Spliceosome Nucleus RNA Splicing, Via Transesterification Reactions Spliceosomal Complex Negative Regulation Of MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Catalytic Step 2 Spliceosome Aminoacyl-tRNA Synthetase Multienzyme Complex Cytoplasmic Stress Granule MRNA 3'-UTR Binding Regulation Of Translation Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization MRNA Stabilization Negative Regulation Of Translation Regulation Of MRNA Stability MRNA Cleavage And Polyadenylation Specificity Factor Complex Regulation Of Primary Metabolic Process Regulation Of RNA Stability Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Paraspeckles Negative Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation CRD-mediated MRNA Stabilization Regulation Of Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA 5'-UTR Binding RNA Transport Positive Regulation Of Gene Expression	RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Translation Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of MRNA Stability Regulation Of RNA Stability Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Translation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of MRNA Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Macromolecule Metabolic Process Extracellular Vesicle Negative Regulation Of Protein Metabolic Process Regulation Of Cell Migration Regulation Of Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Catabolic Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Signal Transduction Negative Regulation Of Endothelial Cell Migration Extracellular Space Regulation Of Angiogenesis Negative Regulation Of Cell Communication
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?