PCAT1 and GRWD1

Number of citations of the paper that reports this interaction (PubMedID 31903119)
55

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		PCAT1	GRWD1
Description		prostate cancer associated transcript 1	glutamate rich WD repeat containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Protein-containing Complex
	Molecular Function		Chromatin Binding DNA Replication Origin Binding RNA Binding Protein Binding Histone Binding
	Biological Process		DNA Replication Nucleosome Assembly Nucleosome Disassembly Ribosome Biogenesis
Pathways
Drugs
Diseases
GWAS		Body mass index ( 25673413) Heel bone mineral density ( 28869591 30598549) Intracranial aneurysm ( 29531279) Lung cancer in never smokers ( 28604730)
Interacting Genes		13 interacting genes: AAMP CASD1 FAF2 FILNC1 GJA10 GRWD1 HNRNPH1 NAV3 PCCB PCLO PDIA3 RPL11 TUFM	10 interacting genes: CDC42 CEBPA ESR1 OGT PCAT1 RPL11 RPL23 SLC25A21-AS1 TP53 USP7
Entrez ID		100750225	83743
HPRD ID			11013
Ensembl ID		ENSG00000253438	ENSG00000105447
Uniprot IDs			Q9BQ67
PDB IDs
Enriched GO Terms of Interacting Partners?			Protein-containing Complex Negative Regulation Of Proteolysis Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Actinomycin D Negative Regulation Of Catabolic Process Response To Actinomycin D Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Transcription Coactivator Binding Regulation Of G1 To G0 Transition Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Protein Stabilization Rhythmic Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Metabolic Process Negative Regulation Of Ubiquitin Protein Ligase Activity Cellular Response To Antibiotic Protein Localization To Organelle Negative Regulation Of Post-translational Protein Modification Negative Regulation Of Ubiquitin-protein Transferase Activity Ubiquitin Ligase Inhibitor Activity Regulation Of Glucose Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Protein Catabolic Process Regulation Of Protein Stability Negative Regulation Of Protein Catabolic Process Cytoplasmic Translation Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Stem Cell Proliferation Negative Regulation Of Transcription By RNA Polymerase II Response To Nutrient Levels Negative Regulation Of Macromolecule Metabolic Process Protein Localization To Nucleus 14-3-3 Protein Binding Intracellular Protein Localization Regulation Of Protein Ubiquitination Positive Regulation Of Signal Transduction By P53 Class Mediator Intracellular Signal Transduction Response To Antibiotic Regulation Of Catalytic Activity Regulation Of Programmed Necrotic Cell Death Negative Regulation Of Metabolic Process
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