CD68

Name	CD68 molecule
Structure	No pdb structure
Interactors	13 interactors: ADRB2 AGR2 AQP6 CFTR CLEC2D KTN1 MAL2 MUC1 PLEKHB2 RALGDS SGTB TMEM179B TOMM6
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Plasma Membrane Endosome Membrane Membrane Cytoplasmic Vesicle Late Endosome Membrane Azurophil Granule Membrane
	Molecular Function	Protein Binding
	Biological Process	Inflammatory Response To Antigenic Stimulus Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Cellular Response To Nutrient Levels Autocrine Signaling Response To Ethanol Cellular Response To Lipopolysaccharide Establishment Of Protein Localization To Organelle Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus
Pathways	Neutrophil degranulation
GWAS	Brain morphology (MOSTest) ( 32665545 ) Heel bone mineral density ( 28869591 ) IgA levels ( 28628107 ) Metabolic syndrome ( 31589552 ) Post bronchodilator FEV1/FVC ratio ( 26634245 ) Refractive error ( 32231278 )
Entrez ID	968
HPRD ID	01093
Ensembl ID	ENSG00000129226
Uniprot IDs	P34810
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Apical Plasma Membrane Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Mini Excitatory Postsynaptic Potential Nitrate Transmembrane Transporter Activity Fluid Transport Water Transport Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Clathrin-coated Endocytic Vesicle Membrane Beta2-adrenergic Receptor Activity Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Positive Regulation Of Anion Channel Activity TRC Complex Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Norepinephrine Binding Chloride Transmembrane Transport Odontogenesis Chloride Transport Protein-folding Chaperone Binding Positive Regulation Of Enamel Mineralization Recycling Endosome Membrane Positive Regulation Of Monoatomic Anion Transport Lung Goblet Cell Differentiation Positive Regulation Of PERK-mediated Unfolded Protein Response