TGS1

Gene Name		trimethylguanosine synthase 1
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Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Small Nuclear Ribonucleoprotein Complex
	Molecular Function	Protein Binding RNA Trimethylguanosine Synthase Activity
	Biological Process	Spliceosomal SnRNP Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated 7-methylguanosine RNA Capping Gene Expression Ribonucleoprotein Complex Biogenesis NcRNA Metabolic Process 7-methylguanosine Cap Hypermethylation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Ribonucleoprotein Complex Import Into Nucleus
Pathways		PPARA activates gene expression Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Metabolism of non-coding RNA REV-ERBA represses gene expression RORA activates circadian gene expression Mitochondrial biogenesis Regulation of cholesterol biosynthesis by SREBP (SREBF) Generic Transcription Pathway snRNP Assembly Transcriptional regulation of white adipocyte differentiation YAP1- and WWTR1 (TAZ)-stimulated gene expression Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis BMAL1:CLOCK,NPAS2 activates circadian gene expression Orphan transporters
Drugs
Diseases
GWAS		Height ( 18391951)
Protein-protein Interactions		6 interactors: COIL CREBBP EED EP300 HNF4A NCOA6
Entrez ID		96764
HPRD ID		07567
Ensembl ID		ENSG00000137574
Uniprot IDs		Q96RS0
PDB IDs		3EGI 3GDH
Enriched GO Terms of Interacting Partners?		N-terminal Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia RNA Biosynthetic Process N-terminal Protein Amino Acid Modification Regulation Of Cellular Response To Heat Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress RNA Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Metabolic Process Gene Expression Cellular Response To Heat Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Type I Interferon Production Chromatin Modification Cellular Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Decreased Oxygen Levels Regulation Of Type I Interferon Production Regulation Of Transcription, DNA-templated Histone H2B Acetylation Regulation Of Nucleic Acid-templated Transcription Cellular Response To Oxygen Levels Regulation Of RNA Biosynthetic Process Response To Heat Histone Acetylation Regulation Of RNA Metabolic Process Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Chromatin Organization Internal Protein Amino Acid Acetylation Nucleobase-containing Compound Metabolic Process Protein Acetylation Notch Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process
Tagcloud ?		accumulate accumulates billion dormancy dosr drastic droplet droplets fatty filled granuloma hspx hypoxic icl1 imports incorporates inside isoniazid latently lipid lipy loaded mtb radiolabeled sequestered tag taqman triacylglycerol utilizes