CD33

Gene Name		CD33 molecule
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Protein Binding Carbohydrate Binding
	Biological Process	Cell Adhesion Signal Transduction Cell-cell Signaling Negative Regulation Of Cell Proliferation
Pathways
Drugs		Gemtuzumab ozogamicin
Diseases
GWAS		Alzheimer's disease ( 18976728) Alzheimer's disease (late onset) ( 21460841)
Protein-protein Interactions		6 interactors: HERC3 KRT31 KRT40 PTPN11 PTPN6 SRC
Entrez ID		945
HPRD ID		01165
Ensembl ID		ENSG00000105383
Uniprot IDs		P20138 Q546G0
PDB IDs
Enriched GO Terms of Interacting Partners?		Abortive Mitotic Cell Cycle T Cell Costimulation Megakaryocyte Development Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Adhesion Positive Regulation Of T Cell Activation Platelet Formation Positive Regulation Of Homotypic Cell-cell Adhesion Platelet Morphogenesis Regulation Of Interferon-gamma-mediated Signaling Pathway Megakaryocyte Differentiation Regulation Of Response To Interferon-gamma Leukocyte Migration Bone Development Positive Regulation Of Cell-cell Adhesion Myeloid Cell Differentiation Regulation Of MAP Kinase Activity Regulation Of T Cell Activation Positive Regulation Of Cell Activation Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Lymphocyte Activation Blood Coagulation Hemostasis Regulation Of Intracellular Transport Response To Peptide Hormone Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Cellular Response To Organonitrogen Compound Response To Peptide Regulation Of Cellular Response To Insulin Stimulus Skeletal System Development Regulation Of Body Fluid Levels Cellular Response To Hormone Stimulus Wound Healing Ephrin Receptor Signaling Pathway Regulation Of Cytokine-mediated Signaling Pathway Regulation Of MAPK Cascade Regulation Of Cell Adhesion Hemopoiesis Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion
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