TNFSF8

Gene Name		tumor necrosis factor (ligand) superfamily, member 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Integral Component Of Plasma Membrane
	Molecular Function	Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding
	Biological Process	Apoptotic Process Immune Response Signal Transduction Cell-cell Signaling Cell Proliferation CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Defense Response To Gram-positive Bacterium
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 21102463 23266558) Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 21297633)
Protein-protein Interactions		2 interactors: ANG TNFRSF8
Entrez ID		944
HPRD ID		04852
Ensembl ID
Uniprot IDs		P32971 Q52M88
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of TRAIL Biosynthetic Process Diacylglycerol Biosynthetic Process Activation Of Phospholipase A2 Activity Positive Regulation Of Phospholipase A2 Activity Negative Regulation Of Cell Proliferation Regulation Of Phospholipase A2 Activity Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Diacylglycerol Metabolic Process Regulation Of Tumor Necrosis Factor Biosynthetic Process RRNA Transcription Oocyte Maturation Response To Abiotic Stimulus Activation Of Protein Kinase B Activity Positive Regulation Of Protein Metabolic Process Negative Regulation Of Smooth Muscle Cell Proliferation Actin Filament Polymerization Oocyte Development Oocyte Differentiation Regulation Of Cell Proliferation Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Cytokine Biosynthetic Process Ovarian Follicle Development Cellular Response To Mechanical Stimulus Positive Regulation Of Phospholipase Activity Oogenesis Regulation Of Endothelial Cell Proliferation Regulation Of Phospholipase Activity Negative Regulation Of Translation Actin Polymerization Or Depolymerization Positive Regulation Of Lipase Activity Regulation Of Tumor Necrosis Factor Production Ovulation Cycle Process Regulation Of Smooth Muscle Cell Proliferation Regulation Of Protein Metabolic Process Neutral Lipid Metabolic Process Protein Polymerization RNA Phosphodiester Bond Hydrolysis Regulation Of Cytokine Biosynthetic Process Female Gonad Development Female Gamete Generation Ovulation Cycle Development Of Primary Female Sexual Characteristics Positive Regulation Of Cellular Metabolic Process Cell Maturation Positive Regulation Of Epithelial Cell Proliferation
Tagcloud ?		abc bcl2af1 bcl2l10 biology casp10 casp14 casp8 cd70 changed cideb cluster correlate fadd hierarchical hrk igf1r mcl1 needle neoadjuvant pathologic profiling prognosis reflect removed substantially therapeutically tunel valuable