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CCNA2
Gene Name
cyclin A2
Image
Gene Ontology Annotations
Cellular Component
Female Pronucleus
Male Pronucleus
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
Protein Binding
Protein Kinase Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Mitotic Nuclear Division
Mitotic G2 DNA Damage Checkpoint
Ras Protein Signal Transduction
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Organ Regeneration
Response To Estradiol
Response To Glucagon
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Fibroblast Proliferation
Cell Division
Pathways
Cellular Senescence
G2/M Transition
Orc1 removal from chromatin
Cyclin E associated events during G1/S transition
Cyclin A/B1 associated events during G2/M transition
G1/S Transition
G2 Phase
Removal of licensing factors from origins
Switching of origins to a post-replicative state
Mitotic G1-G1/S phases
DNA Damage/Telomere Stress Induced Senescence
Synthesis of DNA
Regulation of DNA replication
G0 and Early G1
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
APC/C:Cdc20 mediated degradation of mitotic proteins
Senescence-Associated Secretory Phenotype (SASP)
Regulation of APC/C activators between G1/S and early anaphase
S Phase
APC/C-mediated degradation of cell cycle proteins
Cell Cycle, Mitotic
Orc1 removal from chromatin
SCF(Skp2)-mediated degradation of p27/p21
Regulation of mitotic cell cycle
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Cyclin A:Cdk2-associated events at S phase entry
SCF(Skp2)-mediated degradation of p27/p21
Mitotic G2-G2/M phases
Drugs
Diseases
GWAS
Protein-protein Interactions
50 interactors:
ARID4A
BRCA1
BRCA2
BTG1
CALM1
CDC20
CDC25C
CDC27
CDC6
CDK1
CDK2
CDK3
CDK7
CDKN1A
CDKN1B
CDT1
CKS1B
CKS1BP7
CKS2
DTNBP1
E2F1
E2F3
FEN1
FZR1
HERC5
HIRA
HIST1H1A
HIST1H1B
ITGB3BP
KAT2B
MYBL2
NFYA
PGR
POLA1
PRC1
PSMD4
PTMA
RAD23A
RB1
RBL1
RBL2
RPA1
SKP1
SKP2
SP1
TAF1
TP53
TRAF3IP1
UBTF
USP37
Entrez ID
890
HPRD ID
00453
Ensembl ID
ENSG00000145386
Uniprot IDs
P20248
PDB IDs
1E9H
1FIN
1FVV
1GY3
1H1P
1H1Q
1H1R
1H1S
1H24
1H25
1H26
1H27
1H28
1JST
1JSU
1OGU
1OI9
1OIU
1OIY
1OKV
1OKW
1OL1
1OL2
1P5E
1PKD
1QMZ
1URC
1VYW
2BKZ
2BPM
2C4G
2C5N
2C5O
2C5V
2C5X
2C6T
2CCH
2CCI
2CJM
2I40
2IW6
2IW8
2IW9
2UUE
2UZB
2UZD
2UZE
2UZL
2V22
2WEV
2WFY
2WHB
2WIH
2WIP
2WMA
2WMB
2WPA
2WXV
2X1N
3EID
3EJ1
3EOC
3F5X
4BCK
4BCM
4BCN
4BCP
4EOI
4EOJ
4EOK
4EOL
4EOM
4EON
4EOO
4EOP
4EOQ
4EOR
4EOS
4FX3
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Mitotic Cell Cycle
Cell Cycle Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Mitotic Cell Cycle Process
Regulation Of Cell Cycle
G1/S Transition Of Mitotic Cell Cycle
Organelle Organization
Cell Cycle Checkpoint
Cell Division
Regulation Of Cell Cycle Process
Positive Regulation Of Cellular Metabolic Process
Chromosome Organization
Regulation Of Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Chromatin Organization
Regulation Of Protein Metabolic Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Mitotic Cell Cycle
Mitotic Nuclear Division
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Metabolic Process
Cellular Response To DNA Damage Stimulus
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Cellular Macromolecule Biosynthetic Process
Regulation Of Protein Catabolic Process
Macromolecule Biosynthetic Process
Regulation Of Mitotic Cell Cycle Phase Transition
DNA Damage Checkpoint
Regulation Of Cell Proliferation
Regulation Of Cell Cycle Phase Transition
Mitotic Cell Cycle Checkpoint
Positive Regulation Of Gene Expression
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
Signal Transduction By P53 Class Mediator
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Proteasomal Protein Catabolic Process
G2/M Transition Of Mitotic Cell Cycle
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Nitrogen Compound Metabolic Process
Chromatin Modification
DNA Replication
Positive Regulation Of Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Heterocycle Metabolic Process
Tagcloud
?
calm3
cblb
ccnd3
cdk6
cited1
dems
dok
elk3
fyn
git1
hck
lck
module
modules
nonmodule
p85beta
pdgfra
pib5pa
psd93
ptch2
sam68
sh3kbp1
shc
tgfbr1
tgfbr2
vav2
wilcoxon
yes
zfyve9