DYRK4

Gene Name		dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Peptidyl-tyrosine Phosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: CUL3 DYRK2 FBXO25 MID1 NEDD4 PPP1CC
Entrez ID		8798
HPRD ID		10926
Ensembl ID		ENSG00000010219
Uniprot IDs		B4E1A4 D3JEN2 Q9NR20
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Monoubiquitination Cell Surface Receptor Signaling Pathway Cellular Protein Modification Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Protein Ubiquitination Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein Modification By Small Protein Conjugation Catabolic Process Depurination Trophectodermal Cellular Morphogenesis Protein Polyubiquitination Cellular Macromolecule Catabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Intrinsic Apoptotic Signaling Pathway Cellular Protein Metabolic Process Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Positive Regulation Of Protein Catabolic Process Progesterone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage DNA Dealkylation Involved In DNA Repair Negative Regulation Of Signal Transduction Base-excision Repair, AP Site Formation Positive Regulation Of Mitotic Metaphase/anaphase Transition Protein Localization To Microtubule Glucocorticoid Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of NFAT Protein Import Into Nucleus Regulation Of Signal Transduction Signal Transduction Response To Light Stimulus Protein Targeting To Lysosome Apoptotic Signaling Pathway Embryonic Cleavage Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein Metabolic Process Positive Regulation Of Glycogen Biosynthetic Process Regulation Of Signaling Protein Localization To Lysosome Stress Fiber Assembly Signaling Regulation Of Protein Catabolic Process Negative Regulation Of Transport Cell Communication Positive Regulation Of Chromosome Segregation Deoxyribose Phosphate Catabolic Process Cellular Response To Stress
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