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PARP10
Gene Name
poly (ADP-ribose) polymerase family, member 10
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Golgi Apparatus
Molecular Function
NAD+ ADP-ribosyltransferase Activity
Protein Binding
K63-linked Polyubiquitin Binding
Biological Process
Protein ADP-ribosylation
Negative Regulation Of Gene Expression
Regulation Of Chromatin Assembly
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Protein Import Into Nucleus, Translocation
Negative Regulation Of Viral Genome Replication
Negative Regulation Of Fibroblast Proliferation
Protein Poly-ADP-ribosylation
Protein Auto-ADP-ribosylation
Negative Regulation Of Protein K63-linked Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
9 interactors:
H3F3A
HIST1H3A
HIST1H4A
HIST2H2AC
HIST2H2BE
IKBKG
MYC
PCNA
UBC
Entrez ID
84875
HPRD ID
15100
Ensembl ID
ENSG00000178685
Uniprot IDs
E9PNI7
Q53GL7
PDB IDs
2DHX
3HKV
Enriched GO Terms of Interacting Partners
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DNA Methylation On Cytosine
Chromatin Silencing At RDNA
Nucleosome Assembly
Chromatin Assembly
Nucleosome Organization
Chromatin Assembly Or Disassembly
Chromatin Silencing
Protein-DNA Complex Assembly
DNA Packaging
Chromosome Organization
DNA Methylation
DNA Conformation Change
Negative Regulation Of Gene Expression, Epigenetic
Chromatin Organization
DNA Modification
DNA Replication-dependent Nucleosome Assembly
Gene Silencing
DNA Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Response To Stress
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Negative Regulation Of Gene Expression
Regulation Of Gene Expression, Epigenetic
Cellular Macromolecular Complex Assembly
Negative Regulation Of Biosynthetic Process
MAPK Cascade
DNA Replication-independent Nucleosome Assembly
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Signal Transduction By Phosphorylation
Regulation Of Transcription, DNA-templated
Cellular Response To DNA Damage Stimulus
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Regulation Of RNA Metabolic Process
I-kappaB Kinase/NF-kappaB Signaling
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Nucleobase-containing Compound Metabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Organelle Organization
MyD88-dependent Toll-like Receptor Signaling Pathway
Heterocycle Metabolic Process
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