TRAF7

Gene Name		TNF receptor-associated factor 7, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytosol Plasma Membrane Cytoplasmic Membrane-bounded Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Activation Of MAPKKK Activity Transcription, DNA-templated Apoptotic Process Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of Protein Sumoylation Positive Regulation Of MAPK Cascade Cellular Response To Interleukin-6 Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: CYLD MAP3K3 RIPK4 TRAF6 UBE2D1 UBE2D2 UBE2D4 UBE2K UBE2L3 UBE2L6
Entrez ID		84231
HPRD ID		06977
Ensembl ID		ENSG00000131653
Uniprot IDs		B3KQY7 Q6Q0C0
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Cellular Protein Modification Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Metabolic Process Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Cellular Macromolecule Catabolic Process Proteolysis Protein Metabolic Process Positive Regulation Of Innate Immune Response Ubiquitin-dependent Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Innate Immune Response Toll-like Receptor Signaling Pathway Positive Regulation Of Protein Ubiquitination Immune Response-regulating Signaling Pathway Catabolic Process Protein K11-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Positive Regulation Of Transferase Activity Regulation Of Protein Ubiquitination Protein K63-linked Ubiquitination Immune Response Positive Regulation Of Immune Response Regulation Of I-kappaB Kinase/NF-kappaB Signaling Defense Response Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Type I Interferon Production Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Ubiquitin-protein Transferase Activity
Tagcloud ?		adaptive ap associates brings cytoplasmic humoral identifies ikappab influences innate interacting kappab lys lysosomal member microarray modulator necrosis nemo nf noncanonical p65 physically polyubiquitination promotes rela transducers ubiquitination