HYAL3

Gene Name		hyaluronoglucosaminidase 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Lysosome Cytoplasmic Vesicle
	Molecular Function	Virus Receptor Activity Hyalurononglucosaminidase Activity Hyaluronoglucuronidase Activity
	Biological Process	Carbohydrate Metabolic Process Inflammatory Response Response To Virus Hyaluronan Catabolic Process Response To Antibiotic Cartilage Development Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To UV-B
Pathways		MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Chondroitin sulfate/dermatan sulfate metabolism Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism CS/DS degradation Hyaluronan uptake and degradation Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective CHST14 causes EDS, musculocontractural type Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Hyaluronan metabolism Defective CHST6 causes MCDC1 MPS IIID - Sanfilippo syndrome D Glycogen storage diseases MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective CHST3 causes SEDCJD Defective B3GAT3 causes JDSSDHD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A MPS IV - Morquio syndrome B Defective CHSY1 causes TPBS MPS VII - Sly syndrome Metabolism of carbohydrates MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: DAB1 SLC22A2
Entrez ID		8372
HPRD ID		04948
Ensembl ID		ENSG00000186792
Uniprot IDs		O43820
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Cerebellum Structural Organization Lateral Motor Column Neuron Migration Spinal Cord Motor Neuron Migration Radial Glia Guided Migration Of Purkinje Cell Response To Drug Choline Transport Golgi Localization Negative Regulation Of Astrocyte Differentiation Neurotransmitter Biosynthetic Process Histamine Transport Quaternary Ammonium Group Transport Midgut Development Anatomical Structure Arrangement Negative Regulation Of JAK-STAT Cascade Cell Migration In Hindbrain Neurotransmitter Metabolic Process Regulation Of Astrocyte Differentiation Drug Transmembrane Transport Negative Regulation Of Glial Cell Differentiation Ammonium Transmembrane Transport Organic Cation Transport Drug Transport Adult Walking Behavior Cerebellum Morphogenesis Hindbrain Morphogenesis Ventral Spinal Cord Development Cerebral Cortex Radially Oriented Cell Migration Negative Regulation Of Axonogenesis Ammonium Transport Regulation Of Glial Cell Differentiation Cerebral Cortex Cell Migration Regulation Of JAK-STAT Cascade Negative Regulation Of Cell Morphogenesis Involved In Differentiation Telencephalon Cell Migration Forebrain Cell Migration Regulation Of Gliogenesis Body Fluid Secretion Spinal Cord Development Neurotransmitter Secretion Adult Locomotory Behavior Cerebellum Development Negative Regulation Of Neuron Projection Development Cellular Localization Metencephalon Development Digestive Tract Development Regulation Of Neurotransmitter Levels Dendrite Development Negative Regulation Of Cell Projection Organization Digestive System Development
Tagcloud ?		10a 184a1 184b5 3p21 cacna2d2 closest combinated demethylating deoxycytidine deregulated epigenetically flanking hyal1 hyal2 isoform nprl2 rassf1 rassf1a rassf1c sema3b seventeen silenced spearman tmem115 trichostatin trimethylated tusc2 unmethylated zmynd10