HYAL3

Description		hyaluronidase 3
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Acrosomal Membrane Extracellular Region Lysosome Endosome Early Endosome Endoplasmic Reticulum Plasma Membrane Membrane Cytoplasmic Vesicle Sperm Midpiece
	Molecular Function	Virus Receptor Activity Hyalurononglucosaminidase Activity Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Hyaluronoglucuronidase Activity
	Biological Process	Ovarian Follicle Atresia Carbohydrate Metabolic Process Inflammatory Response Single Fertilization Penetration Of Zona Pellucida Response To Virus Hyaluronan Catabolic Process Response To Antibiotic Cartilage Development Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To UV-B Negative Regulation Of Ovarian Follicle Development Positive Regulation Of Acrosomal Vesicle Exocytosis
Pathways		CS/DS degradation Hyaluronan degradation
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Basophil count ( 32888494) Body mass index ( 29273807) Schizophrenia ( 28991256) Sleep duration (short sleep) ( 30846698)
Interacting Genes		4 interacting genes: BOLL CAMK2A DAB1 SLC22A2
Entrez ID		8372
HPRD ID		04948
Ensembl ID		ENSG00000186792
Uniprot IDs		O43820
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Receptor Signaling Pathway Via JAK-STAT Cell Surface Receptor Signaling Pathway Via STAT Cell Surface Receptor Signaling Pathway Via JAK-STAT Peptidyl-threonine Autophosphorylation Calcium- And Calmodulin-dependent Protein Kinase Complex Regulation Of Endocannabinoid Signaling Pathway Lateral Motor Column Neuron Migration Cerebellum Structural Organization Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Spinal Cord Motor Neuron Migration Radial Glia Guided Migration Of Purkinje Cell Acetylcholine Transport Histamine Uptake Pyrimidine Nucleoside Transmembrane Transporter Activity Spermidine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Amine Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity Spermidine Transmembrane Transporter Activity L-arginine Import Across Plasma Membrane Putrescine Transmembrane Transporter Activity Thiamine Transmembrane Transport Acetylcholine Transmembrane Transporter Activity Radial Glia-guided Pyramidal Neuron Migration Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Glutamate Receptor Binding Toxin Transmembrane Transporter Activity Choline Transmembrane Transporter Activity Polyamine Transmembrane Transport Ventral Spinal Cord Development Serotonin Uptake Choline Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Norepinephrine Transport Histamine Transport L-arginine Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity L-arginine Transmembrane Transport Amine Transport Catecholamine Uptake Dopamine Uptake Cell Migration In Hindbrain Reelin-mediated Signaling Pathway
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