NDFIP1

Gene Name		Nedd4 family interacting protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Extracellular Region Cell Cortex Endosome Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Signal Transducer Activity Protein Binding WW Domain Binding
	Biological Process	Regulation Of Myeloid Leukocyte Differentiation Negative Regulation Of Type 2 Immune Response Cellular Iron Ion Homeostasis Signal Transduction Negative Regulation Of Gene Expression Positive Regulation Of Protein Ubiquitination Negative Regulation Of Transporter Activity Negative Regulation Of Interleukin-4 Production Negative Regulation Of T Cell Proliferation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Lymphocyte Differentiation Positive Regulation Of Protein Catabolic Process Negative Regulation Of Isotype Switching To IgE Isotypes Regulation Of Isotype Switching To IgG Isotypes Negative Regulation Of Inflammatory Response Negative Regulation Of Protein Transport
Pathways
Drugs
Diseases
GWAS		Asthma ( 22561531) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 21833088)
Protein-protein Interactions		2 interactors: NEDD4 PTEN
Entrez ID		80762
HPRD ID		14816
Ensembl ID		ENSG00000131507
Uniprot IDs		Q9BT67
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Dendrite Morphogenesis Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Dendrite Development Synapse Organization Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Negative Regulation Of Synaptic Vesicle Clustering Development Involved In Symbiotic Interaction Positive Regulation Of Protein Catabolic Process Regulation Of Membrane Potential Postsynaptic Density Assembly Activation Of APC-Cdc20 Complex Activity Negative Regulation Of Presynaptic Membrane Organization Response To Metal Ion Negative Regulation Of Dendritic Spine Morphogenesis Regulation Of Neuron Projection Development Regulation Of Protein Catabolic Process Negative Regulation Of Transport Negative Regulation Of Ribosome Biogenesis Central Nervous System Myelin Maintenance Blood Vessel Morphogenesis Regulation Of Presynaptic Membrane Organization Response To Inorganic Substance Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Rhythmic Synaptic Transmission Negative Regulation Of Dendritic Spine Development Progesterone Receptor Signaling Pathway Blood Vessel Development Heart Development Vasculature Development Activation Of Anaphase-promoting Complex Activity Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Synapse Maturation Regulation Of Neuron Differentiation Male Mating Behavior Positive Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Excitatory Postsynaptic Membrane Potential Glucocorticoid Receptor Signaling Pathway Presynaptic Membrane Assembly Negative Regulation Of Dendrite Morphogenesis Locomotor Rhythm Negative Regulation Of Myelination Presynaptic Membrane Organization Regulation Of Neurogenesis Protein Targeting To Lysosome Inositol Phosphate Dephosphorylation Negative Regulation Of Phagocytosis Negative Regulation Of Sodium Ion Transport
Tagcloud ?		ago autonomous called concept decades deleterious discovered ev exosomes exported favouring guises indeed isoform laboratories mediating naked nearly nedd4 packaged packaging propagate pten recipient revolutionary secreted ubiquitination versions vesicles