CDK5RAP3

Gene Name		CDK5 regulatory subunit associated protein 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endomembrane System Membrane Protein Complex
	Molecular Function	Protein Binding Protein Kinase Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Mitotic Cell Cycle Brain Development Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Ufmylation
Pathways
Drugs
Diseases
GWAS		Epilepsy (generalized) ( 22949513)
Protein-protein Interactions		11 interactors: CDK5R1 CREBBP CRMP1 DGCR14 DISC1 FKBP6 KPNA2 SRPRB TAB1 TAX1BP3 TSPYL4
Entrez ID		80279
HPRD ID		12190
Ensembl ID		ENSG00000108465
Uniprot IDs		B7Z6N4 F5H3I5 Q96JB5
PDB IDs
Enriched GO Terms of Interacting Partners?		Cerebral Cortex Radially Oriented Cell Migration Positive Regulation Of Protein Modification Process Cerebral Cortex Cell Migration Superior Olivary Nucleus Maturation Telencephalon Cell Migration Forebrain Cell Migration Positive Regulation Of Protein Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Kinase Activity Cell Surface Receptor Signaling Pathway Pons Maturation N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transferase Activity Positive Regulation Of Metabolic Process Serine Phosphorylation Of STAT3 Protein Cerebral Cortex Development Germ-line Stem Cell Maintenance Serine Phosphorylation Of STAT Protein Neuron Migration Signal Transduction Pyrimidine Nucleobase Catabolic Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Catalytic Activity Negative Regulation Of Protein Localization To Cell Surface Activation Of MAPKKK Activity Pallium Development Regulation Of Protein Kinase Activity
Tagcloud ?		anchors aspartate ataxin atx1 autonomous bergmann cerebellum collectively consistently downregulated eventually glia glutamate helix interacting knockin maxer mediates mediating mutant named purkinje represses repression rescues sca1 strengthened transporter vulnerability