EDEM3

Description		ER degradation enhancing alpha-mannosidase like protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase Activity Calcium Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Response To Unfolded Protein Endoplasmic Reticulum Unfolded Protein Response ERAD Pathway Ubiquitin-dependent Glycoprotein ERAD Pathway Endoplasmic Reticulum Mannose Trimming
Pathways		ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body size at age 10 ( 32376654) Cerebrospinal fluid immune biomarker levels ( 32066700) Estimated glomerular filtration rate ( 31152163) Liver enzyme levels (alkaline phosphatase) ( 33972514) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 24871463) Urinary albumin-to-creatinine ratio ( 31511532 31630189) Waist circumference adjusted for body mass index ( 34021172)
Novel Interacting Genes		2 novel interacting genes: CACYBP METTL13
Interacting Genes		2 interacting genes: TRA TXNDC5
Entrez ID		80267
HPRD ID		10724
Ensembl ID		ENSG00000116406
Uniprot IDs		A0A8J8YX80 Q9BZQ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Detection Of Tumor Cell T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Alpha-beta T Cell Receptor Complex Immune Response To Tumor Cell T Cell Mediated Cytotoxicity T Cell Receptor Complex Beta-catenin Destruction Complex Nuclear Envelope Lumen S100 Protein Binding Response To Growth Hormone Intracellular Organelle Lumen Protein Disulfide Isomerase Activity Protein-disulfide Reductase Activity Protein-lysine N-methyltransferase Activity
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