RNF34

Gene Name		ring finger protein 34, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Endomembrane System Nuclear Speck
	Molecular Function	P53 Binding Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity Phosphatidylinositol Phosphate Binding
	Biological Process	Protein Ubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Cold Protein K48-linked Ubiquitination Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Oxygen Metabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		9 interactors: APP APPBP2 DNAJA3 NOD1 PHF7 TRIM23 UBE2D2 UBE2F UBE2H
Entrez ID		80196
HPRD ID		10509
Ensembl ID		ENSG00000170633
Uniprot IDs		Q969K3
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Peptidase Activity Protein Modification By Small Protein Conjugation Regulation Of Innate Immune Response Protein K48-linked Ubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Innate Immune Response Positive Regulation Of Proteolysis Neuromuscular Junction Development TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Endopeptidase Activity Protein Metabolic Process Regulation Of Peptidase Activity Toll-like Receptor 4 Signaling Pathway Interleukin-8 Biosynthetic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Immune Response Zymogen Activation Defense Response Toll-like Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Ubiquitination Positive Regulation Of Cysteine-type Endopeptidase Activity Cellular Protein Metabolic Process Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Endopeptidase Activity Innate Immune Response-activating Signal Transduction Positive Regulation Of Catalytic Activity Collateral Sprouting In Absence Of Injury Activation Of Innate Immune Response Regulation Of Proteolysis Interleukin-8 Production Protein Polyubiquitination Synapse Organization Regulation Of Protein Kinase Activity Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Innate Immune Response Cellular Protein Modification Process Regulation Of Kinase Activity Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Axon Choice Point Recognition Activation-induced Cell Death Of T Cells
Tagcloud ?		aims blotting candidate confirm diaminopimelic downregulated e3 glutamyl glutathione gst hybrid immunoprecipitation interfering ip kappa ligase meso nod1 nucleotide oligomerization partner promoted pull regulator regulatory transfection transferase ubiquitination yeast