SVEP1

Gene Name		sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoplasm Membrane
	Molecular Function	Calcium Ion Binding
	Biological Process	Cell Adhesion
Pathways
Drugs
Diseases
GWAS		Longevity ( 20834067) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Protein-protein Interactions		5 interactors: ATF7IP SKIL SMAD3 SMAD9 ZFYVE9
Entrez ID		79987
HPRD ID		12942
Ensembl ID		ENSG00000165124
Uniprot IDs		B3KQM1 Q4LDE5 Q5JB40
PDB IDs
Enriched GO Terms of Interacting Partners?		Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway SMAD Protein Complex Assembly Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cellular Response To Growth Factor Stimulus Enzyme Linked Receptor Protein Signaling Pathway Lens Fiber Cell Differentiation Lens Development In Camera-type Eye Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Positive Regulation Of Transforming Growth Factor Beta3 Production Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Arrest Transcription, DNA-templated Kidney Epithelium Development Positive Regulation Of Cell Differentiation Positive Regulation Of Cell Morphogenesis Involved In Differentiation RNA Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Response To Organic Substance Evasion Or Tolerance Of Host Defenses By Virus Positive Regulation Of Apoptotic Signaling Pathway Protein Complex Assembly Regulation Of Gene Expression, Epigenetic Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Transcription, DNA-templated Epithelium Development DNA-templated Transcription, Initiation Negative Regulation Of Signal Transduction Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Extracellular Matrix Assembly Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Primary MiRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cell Surface Receptor Signaling Pathway Response To Hypoxia
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