DYNC2H1

Description		dynein cytoplasmic 2 heavy chain 1
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytoskeleton Cytoplasmic Dynein Complex Microtubule Plasma Membrane Cilium Axoneme Membrane Dynein Complex Motile Cilium Cell Projection Apical Part Of Cell Extracellular Exosome Ciliary Tip 9+2 Motile Cilium
	Molecular Function	Nucleotide Binding Cytoskeletal Motor Activity Protein Binding ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Kidney Development Microtubule-based Movement Golgi Organization Determination Of Left/right Symmetry Heart Development Dorsal/ventral Pattern Formation Protein Processing Spinal Cord Motor Neuron Differentiation Central Nervous System Neuron Differentiation Cell Projection Organization Neuron Differentiation Embryonic Limb Morphogenesis Forebrain Development Intraciliary Retrograde Transport Positive Regulation Of Smoothened Signaling Pathway Cilium Assembly Cilium Movement Involved In Cell Motility Coronary Vasculature Development Protein Localization To Cilium Non-motile Cilium Assembly
Pathways		Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases		Asphyxiating thoracic dystrophy; Jeune syndrome Short rib-polydactyly syndrome
GWAS		Adult body size ( 32376654) Coronary artery disease ( 32469254 33020668) Diisocyanate-induced asthma ( 25918132) Response to lurasidone in schizophrenia ( 29730043) Small-cell lung cancer (survival) ( 21118971) Spine bone mineral density and alcohol drinking ( 28012008) Toenail selenium levels ( 25343990) Tuberculosis ( 24057671)
Novel Interacting Genes		2 novel interacting genes: ANGPTL5 CARD18
Interacting Genes		4 interacting genes: DYNC2LI1 MTNR1B PAXIP1 RNF10
Entrez ID		79659
HPRD ID		10344
Ensembl ID		ENSG00000187240
Uniprot IDs		Q8NCM8
PDB IDs		4RH7 8RGG 8RGH
Enriched GO Terms of Interacting Partners?
Tagcloud ?