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WNT2
Gene Name
wingless-type MMTV integration site family member 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Proteinaceous Extracellular Matrix
Extracellular Space
Cytoplasm
Plasma Membrane
Extracellular Matrix
Molecular Function
Frizzled Binding
Cytokine Activity
Protein Binding
Receptor Agonist Activity
Biological Process
Positive Regulation Of Endothelial Cell Proliferation
Positive Regulation Of Mesenchymal Cell Proliferation
Lens Development In Camera-type Eye
Cell-cell Signaling
Positive Regulation Of Cell Proliferation
Wnt Signaling Pathway
Neuron Differentiation
Lung Development
Cell Fate Commitment
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Fibroblast Proliferation
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Atrial Cardiac Muscle Tissue Morphogenesis
Positive Regulation Of Cardiac Muscle Cell Proliferation
Canonical Wnt Signaling Pathway
Cardiac Epithelial To Mesenchymal Transition
Lung Induction
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Labyrinthine Layer Blood Vessel Development
Iris Morphogenesis
Mammary Gland Epithelium Development
Cellular Response To Retinoic Acid
Cellular Response To Transforming Growth Factor Beta Stimulus
Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974
Signaling by Wnt
Signaling by WNT in cancer
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
WNT ligand biogenesis and trafficking
Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS
Dupuytren's disease (
21732829
)
Response to platinum-based chemotherapy in non-small-cell lung cancer (
22872573
)
Protein-protein Interactions
8 interactors:
AQP5
FZD1
FZD9
HCK
RRAGC
SFRP1
UQCR11
WNT3A
Entrez ID
7472
HPRD ID
00999
Ensembl ID
ENSG00000105989
Uniprot IDs
A4D0V1
P09544
PDB IDs
Enriched GO Terms of Interacting Partners
?
Canonical Wnt Signaling Pathway
Non-canonical Wnt Signaling Pathway
Axis Elongation Involved In Somitogenesis
Wnt Signaling Pathway
Regulation Of Embryonic Development
Positive Regulation Of Canonical Wnt Signaling Pathway
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure
Osteoblast Differentiation
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Cellular Response To Acid Chemical
Regulation Of Catenin Import Into Nucleus
Regulation Of Organ Morphogenesis
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Stem Cell Differentiation
Axis Elongation
Ossification
Negative Regulation Of BMP Signaling Pathway
Regulation Of Wnt Signaling Pathway
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Neuroblast Proliferation
Organ Morphogenesis
Cellular Response To Lipid
Regulation Of BMP Signaling Pathway
Somitogenesis
Negative Regulation Of Canonical Wnt Signaling Pathway Involved In Controlling Type B Pancreatic Cell Proliferation
Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Controlling Type B Pancreatic Cell Proliferation
Respiratory Burst After Phagocytosis
Convergent Extension Involved In Somitogenesis
Negative Regulation Of Heart Induction By Canonical Wnt Signaling Pathway
Positive Regulation Of Mesodermal Cell Fate Specification
Stromal-epithelial Cell Signaling Involved In Prostate Gland Development
Stem Cell Proliferation
Negative Regulation Of Developmental Growth
Cellular Response To Organonitrogen Compound
Regulation Of Cell Morphogenesis
Growth
Somite Development
Positive Regulation Of Signal Transduction
Regulation Of Cytoskeleton Organization
Negative Regulation Of Cell Morphogenesis Involved In Differentiation
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Palate Development
Neural Precursor Cell Proliferation
Negative Regulation Of Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification
Regulation Of Cardiac Cell Fate Specification
Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment
Tagcloud
?
abcb1b
administrated
brosis
colla1
corroborated
dkk1
dkk2
dkk3
dkk4
fi
frizzled
frzb
fz1
fz5
fz7
nano
nephrotoxicity
osteopontin
sfrp
tio2
wnt1
wnt10a
wnt11
wnt3
wnt4
wnt5a
wnt6
wnt7a
wnt9a