UQCRC2

Name	ubiquinol-cytochrome c reductase core protein 2
Structure
Novel Interactors	1 novel interactors: EPHB1
Interactors	3 interactors: CACNA1A RTN4 UQCRC1
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex III
	Molecular Function	Metalloendopeptidase Activity Protein Binding Metal Ion Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Proteolysis Aerobic Respiration Cellular Respiration
Pathways	Respiratory electron transport Mitochondrial protein degradation Complex III assembly Complex III assembly
Drugs	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
GWAS	No GWAS studies recorded
Entrez ID	7385
HPRD ID	01876
Ensembl ID	ENSG00000140740
Uniprot IDs	P22695
PDB IDs	5XTE 5XTH 5XTI
GO Terms Enriched among Interactors ?	Modulation Of Chemical Synaptic Transmission Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Cell Recognition Cell Projection Optic Nerve Morphogenesis Regulation Of Cell Junction Assembly Negative Regulation Of Skeletal Muscle Cell Proliferation Regulation Of Synapse Assembly Negative Regulation Of Satellite Cell Differentiation Hindbrain Tangential Cell Migration Negative Regulation Of Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Satellite Cell Activation Quinol-cytochrome-c Reductase Activity Cell Migration Involved In Vasculogenesis Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Branching Morphogenesis Of A Nerve Positive Regulation Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Toll-like Receptor 9 Signaling Pathway Intracellular Sphingolipid Homeostasis Endoplasmic Reticulum Tubular Network Formation Central Nervous System Vasculogenesis Endoplasmic Reticulum Tubular Network Membrane Negative Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Synapse Organization Ubiquitin Protein Ligase Binding Endoplasmic Reticulum Tubular Network Membrane Organization Cerebral Cortex Radial Glia-guided Migration Positive Regulation Of Artery Morphogenesis Neuronal Cell Body Axon Guidance Receptor Activity Protein-containing Complex Binding Respiratory Chain Complex III Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Respiratory Chain Complex Regulation Of Toll-like Receptor 9 Signaling Pathway Regulation Of Artery Morphogenesis Positive Regulation Of Hepatocyte Proliferation Nuclear Pore Complex Assembly Cell Migration In Hindbrain High Voltage-gated Calcium Channel Activity Regulation Of Skeletal Muscle Cell Proliferation Transmembrane-ephrin Receptor Activity Immunological Synapse Formation Cranial Nerve Morphogenesis Dendritic Spine Development Regulation Of Skeletal Muscle Satellite Cell Proliferation Regulation Of Nervous System Development Ephrin Receptor Activity