UQCRC2

Description		ubiquinol-cytochrome c reductase core protein 2
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex III
	Molecular Function	Metalloendopeptidase Activity Protein Binding Metal Ion Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Proteolysis Aerobic Respiration Cellular Respiration
Pathways		Respiratory electron transport Mitochondrial protein degradation Complex III assembly Complex III assembly
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: EPHB1
Interacting Genes		3 interacting genes: CACNA1A RTN4 UQCRC1
Entrez ID		7385
HPRD ID		01876
Ensembl ID		ENSG00000140740
Uniprot IDs		P22695
PDB IDs		5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Modulation Of Chemical Synaptic Transmission Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Cell Recognition Cell Projection Optic Nerve Morphogenesis Regulation Of Cell Junction Assembly Negative Regulation Of Skeletal Muscle Cell Proliferation Regulation Of Synapse Assembly Negative Regulation Of Satellite Cell Differentiation Hindbrain Tangential Cell Migration Negative Regulation Of Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Satellite Cell Activation Quinol-cytochrome-c Reductase Activity Cell Migration Involved In Vasculogenesis Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Branching Morphogenesis Of A Nerve Positive Regulation Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Toll-like Receptor 9 Signaling Pathway Intracellular Sphingolipid Homeostasis Endoplasmic Reticulum Tubular Network Formation Central Nervous System Vasculogenesis Endoplasmic Reticulum Tubular Network Membrane Negative Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Synapse Organization Ubiquitin Protein Ligase Binding Endoplasmic Reticulum Tubular Network Membrane Organization Cerebral Cortex Radial Glia-guided Migration Positive Regulation Of Artery Morphogenesis Neuronal Cell Body Axon Guidance Receptor Activity Protein-containing Complex Binding Respiratory Chain Complex III Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Respiratory Chain Complex Regulation Of Toll-like Receptor 9 Signaling Pathway Regulation Of Artery Morphogenesis Positive Regulation Of Hepatocyte Proliferation Nuclear Pore Complex Assembly Cell Migration In Hindbrain High Voltage-gated Calcium Channel Activity Regulation Of Skeletal Muscle Cell Proliferation Transmembrane-ephrin Receptor Activity Immunological Synapse Formation Cranial Nerve Morphogenesis Dendritic Spine Development Regulation Of Skeletal Muscle Satellite Cell Proliferation Regulation Of Nervous System Development Ephrin Receptor Activity
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