TPO

Gene Name		thyroid peroxidase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Mitochondrion Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Iodide Peroxidase Activity Peroxidase Activity Calcium Ion Binding Heme Binding
	Biological Process	Thyroid Hormone Generation Response To Oxidative Stress Cellular Nitrogen Compound Metabolic Process Embryonic Hemopoiesis Hormone Biosynthetic Process Hydrogen Peroxide Catabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Amine-derived hormones Thyroxine biosynthesis Metabolism of amino acids and derivatives
Drugs		Carbimazole Dextrothyroxine Propylthiouracil Methimazole
Diseases
GWAS
Protein-protein Interactions		2 interactors: DUOX1 TXNDC11
Entrez ID		7173
HPRD ID		06000
Ensembl ID		ENSG00000115705
Uniprot IDs		P07202 Q502Y3 Q6P534
PDB IDs
Enriched GO Terms of Interacting Partners?		Cuticle Development Hydrogen Peroxide Biosynthetic Process Superoxide Anion Generation Thyroid Hormone Generation Hydrogen Peroxide Catabolic Process Thyroid Hormone Metabolic Process Hydrogen Peroxide Metabolic Process Superoxide Metabolic Process Hormone Biosynthetic Process Phenol-containing Compound Metabolic Process Reactive Oxygen Species Metabolic Process Cell Redox Homeostasis Response To CAMP
Tagcloud ?		125i anaemia blasts count counts deranged equilibrium excess fmol immunoassay inversely irrespective mds megakaryocyte megakaryocytes metabolizes normals operate plasma platelet quite ra raeb refractory smaller sparse syndromes thrombocytopenia thrombopoietin