TCF21

Gene Name		transcription factor 21
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Histone Deacetylase Binding BHLH Transcription Factor Binding Protein Dimerization Activity Androgen Receptor Binding E-box Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Ureteric Bud Development Branching Involved In Ureteric Bud Morphogenesis Morphogenesis Of A Branching Structure Kidney Development Vasculature Development Transcription, DNA-templated Sex Determination Branchiomeric Skeletal Muscle Development Epithelial Cell Differentiation Glomerulus Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Lung Alveolus Development Spleen Development Embryonic Digestive Tract Morphogenesis Reproductive Structure Development Gland Development Sertoli Cell Differentiation Palate Development Lung Morphogenesis Lung Vasculature Development Bronchiole Development Diaphragm Development Respiratory System Development Negative Regulation Of Androgen Receptor Signaling Pathway Metanephric Mesenchymal Cell Differentiation Metanephric Glomerular Capillary Formation
Pathways
Drugs
Diseases
GWAS		Coronary heart disease ( 22751097 21378990)
Protein-protein Interactions		7 interactors: APEX1 APLP1 GTF3C5 HOXB6 KLF15 LMO4 TCF3
Entrez ID		6943
HPRD ID		04493
Ensembl ID		ENSG00000118526
Uniprot IDs		O43680
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Organ Development Developmental Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process System Development Posttranscriptional Regulation Of Gene Expression Cellular Response To Organonitrogen Compound Multicellular Organismal Development Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Cellular Response To Norepinephrine Stimulus Response To Organonitrogen Compound Transcription From RNA Polymerase II Promoter 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Axial Mesoderm Morphogenesis Response To Norepinephrine Negative Regulation Of Cellular Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Immunoglobulin V(D)J Recombination TRNA Transcription DNA Recombination Central Nervous System Development Anterior/posterior Pattern Specification Nervous System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Axial Mesoderm Development Cellular Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis B Cell Lineage Commitment Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
Tagcloud ?		biologic clustering commitment derivation deviant dissemination etiologies evasion fallopian fimbrial fn1 hgsc homeostatic incidences metastasize modules niche pax8 peg3 quiescence slug sparc speculated speculation subsistence survive thbs2 theme totally