TBX2

Gene Name		T-box 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Outflow Tract Septum Morphogenesis Outflow Tract Morphogenesis Endocardial Cushion Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Transcription, DNA-templated Muscle Cell Fate Determination Cell Aging Positive Regulation Of Cell Proliferation Aorta Morphogenesis Atrioventricular Canal Development Embryonic Digit Morphogenesis Negative Regulation Of Transcription, DNA-templated Embryonic Camera-type Eye Morphogenesis Cardiac Muscle Tissue Development Palate Development Positive Regulation Of Cardiac Muscle Cell Proliferation Pharynx Development Developmental Growth Involved In Morphogenesis Mammary Placode Formation Cellular Senescence Negative Regulation Of Heart Looping Negative Regulation Of Cardiac Chamber Formation
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Height ( 20881960 19893584 18391951)
Protein-protein Interactions		3 interactors: CEBPE LZTR1 NKX2-5
Entrez ID		6909
HPRD ID		02850
Ensembl ID		ENSG00000121068
Uniprot IDs		Q13207
PDB IDs
Enriched GO Terms of Interacting Partners?		Purkinje Myocyte Differentiation Atrioventricular Node Cell Fate Commitment Right Ventricular Cardiac Muscle Tissue Morphogenesis Atrioventricular Node Cell Development Apoptotic Process Involved In Heart Morphogenesis Atrioventricular Node Development Positive Regulation Of Voltage-gated Calcium Channel Activity Proepicardium Development Pulmonary Myocardium Development Bundle Of His Development Atrial Cardiac Muscle Cell Development Embryonic Heart Tube Left/right Pattern Formation Septum Secundum Development Cardiac Muscle Cell Fate Commitment Ventricular Cardiac Myofibril Assembly Positive Regulation Of Cardioblast Differentiation Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Cardiac Ventricle Formation Negative Regulation Of Myotube Differentiation Cardiac Chamber Formation Ventricular Trabecula Myocardium Morphogenesis Cardiac Conduction System Development Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription Via Serum Response Element Binding Negative Regulation Of Striated Muscle Cell Apoptotic Process Outflow Tract Septum Morphogenesis Hemopoiesis Heart Trabecula Formation Adult Heart Development Positive Regulation Of DNA-templated Transcription, Initiation Muscle Cell Fate Commitment Venous Blood Vessel Development Atrial Septum Morphogenesis Cardiac Right Ventricle Morphogenesis Macrophage Differentiation Ventricular Cardiac Muscle Cell Development Negative Regulation Of Striated Muscle Cell Differentiation Regulation Of Voltage-gated Calcium Channel Activity Immune System Development Atrial Septum Development Pharyngeal System Development Left/right Pattern Formation Regulation Of DNA-templated Transcription, Initiation Cardiac Myofibril Assembly Cardiac Muscle Cell Proliferation Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Cytokine Biosynthetic Process Apoptotic Process Involved In Morphogenesis Thyroid Gland Development Heart Trabecula Morphogenesis
Tagcloud ?		biventricle bv cardiomyogenic circuits combinatorial coordinately cpcs dimethylation dissect h3k27 h3k4 hampered hand1 hey hlhs hypoplastic ips maldevelopment malformations nkx2 notch1 nppa pluripotency pluripotent reconstitute reprogrammed signatures sre tnnt2