TBX2

Name	T-box transcription factor 2
Structure	No pdb structure
Interactors	12 interactors: ATXN1L CEBPE CIDEB CNOT2 CYSRT1 KRTAP6-3 LMO2 LZTR1 MEIS2 NKX2-5 TNPO2 TTC19
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Histone Deacetylase Binding Sequence-specific DNA Binding DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Heart Looping Heart Morphogenesis Outflow Tract Septum Morphogenesis Outflow Tract Morphogenesis Endocardial Cushion Morphogenesis Endocardial Cushion Formation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Apoptotic Process Notch Signaling Pathway Muscle Cell Fate Determination Regulation Of Heart Contraction Fibroblast Growth Factor Receptor Signaling Pathway Neurogenesis Response To Retinoic Acid Embryonic Heart Tube Development Aorta Morphogenesis Atrioventricular Canal Development Embryonic Digit Morphogenesis Pigment Metabolic Process Involved In Pigmentation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Embryonic Camera-type Eye Morphogenesis Cardiac Muscle Tissue Development Smooth Muscle Cell Differentiation Roof Of Mouth Development Pharyngeal System Development Positive Regulation Of Cardiac Muscle Cell Proliferation Cardiac Muscle Cell Myoblast Differentiation Epithelial Tube Branching Involved In Lung Morphogenesis Developmental Growth Involved In Morphogenesis Mammary Placode Formation Mesenchymal Cell Proliferation Involved In Lung Development Cellular Response To Dexamethasone Stimulus Ureteric Peristalsis Cochlea Morphogenesis Cellular Senescence Melanocyte Proliferation Negative Regulation Of Heart Looping Negative Regulation Of Cardiac Chamber Formation Positive Regulation Of Cell Cycle G1/S Phase Transition Cardiac Jelly Development Atrioventricular Canal Morphogenesis Negative Regulation Of Cellular Senescence
Pathways	Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
GWAS	Age-related hearing impairment ( 34108613 ) Anthropometric traits ( 30166351 ) Anthropometric traits (multi-trait analysis) ( 30166351 ) Chloride levels ( 29403010 ) Chronic kidney disease ( 20383146 ) Circulating fibroblast growth factor 23 levels ( 30217807 ) Corneal hysteresis ( 32716492 ) Corneal resistance factor ( 32716492 ) Coronary artery disease ( 29212778 ) Creatinine levels ( 31015462 20383145 ) Diastolic blood pressure ( 30487518 27618448 27618447 27841878 ) Estimated glomerular filtration rate ( 31015462 ) Height ( 19893584 18391951 20881960 ) Hypertension ( 30487518 27618447 ) Kidney volume ( 34128465 ) Mean arterial pressure ( 27618448 30487518 26390057 ) Potassium levels ( 29403010 ) Pulse pressure ( 27841878 27618447 ) Refractive error ( 32231278 ) Sitting height ratio ( 25865494 ) Spontaneous preterm birth without premature rupture of membranes ( 31194736 ) Systolic blood pressure ( 30487518 28739976 27618447 27618448 27841878 ) Waist circumference adjusted for body mass index ( 34021172 )
Entrez ID	6909
HPRD ID	02850
Ensembl ID	ENSG00000121068
Uniprot IDs	Q13207
PDB IDs	Not available