ABCC8

Gene Name		ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	ATP Binding Sulfonylurea Receptor Activity Potassium Ion Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Ion Channel Binding
	Biological Process	Carbohydrate Metabolic Process Energy Reserve Metabolic Process Potassium Ion Transport Signal Transduction Synaptic Transmission Small Molecule Metabolic Process Regulation Of Insulin Secretion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Inwardly rectifying K+ channels ABC-family proteins mediated transport Integration of energy metabolism ATP sensitive Potassium channels Regulation of insulin secretion Potassium Channels
Drugs		Adenosine triphosphate Glimepiride Chlorpropamide Nateglinide Repaglinide Glyburide Glipizide Gliclazide Tolbutamide Gliquidone Mitiglinide Glycodiazine
Diseases
GWAS
Protein-protein Interactions		4 interactors: CRYBB1 ENSA KCNJ11 KCNJ8
Entrez ID		6833
HPRD ID		02741
Ensembl ID		ENSG00000006071
Uniprot IDs		Q09428
PDB IDs
Enriched GO Terms of Interacting Partners?		Potassium Ion Import Response To Glucose Potassium Ion Transmembrane Transport Response To Carbohydrate Regulation Of Insulin Secretion Potassium Ion Transport Regulation Of Peptide Hormone Secretion Regulation Of Hormone Secretion Cellular Response To Nicotine Regulation Of Protein Secretion Regulation Of Ion Transmembrane Transport Synaptic Transmission Regulation Of Ion Transport Regulation Of Protein Transport Regulation Of Secretion Response To ATP Response To Organic Substance Monovalent Inorganic Cation Transport Regulation Of Establishment Of Protein Localization Positive Regulation Of Cation Channel Activity Vasodilation Response To Ischemia Response To PH Response To Testosterone Regulation Of Protein Localization Response To Nicotine Cellular Response To Alkaloid Negative Regulation Of Insulin Secretion Metal Ion Transport Response To Lipid Negative Regulation Of Peptide Secretion Response To Organic Cyclic Compound Response To Exogenous DsRNA Cell-cell Signaling Positive Regulation Of Ion Transmembrane Transporter Activity Cation Transmembrane Transport Positive Regulation Of Transporter Activity Cellular Response To Glucose Stimulus Regulation Of Cellular Localization Negative Regulation Of Hormone Secretion Response To DsRNA Regulation Of Blood Vessel Size Regulation Of Tube Size Cellular Glucose Homeostasis Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Cellular Response To Carbohydrate Stimulus Neurological System Process Cation Transport Negative Regulation Of Protein Secretion
Tagcloud ?		2kd antigenic antigens atp2a2 autoantibodies candidates cd8 copyright destruction encoded glucagon goal infiltrating islet islets min6 nod pancreatic pathogenesis pcsk2 peg3 producing proglucagon protected recognize reserved rights scg2 specificities