SPINT1

Description		serine peptidase inhibitor, Kunitz type 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity
	Biological Process	Neural Tube Closure Embryonic Placenta Development Epidermis Development Extracellular Matrix Organization Positive Regulation Of Glial Cell Differentiation Epithelium Development Branching Involved In Labyrinthine Layer Morphogenesis Placenta Blood Vessel Development Cellular Response To BMP Stimulus Negative Regulation Of Neural Precursor Cell Proliferation
Pathways		MET Receptor Activation Signaling by MST1
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Malaria ( 31844061) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		23 interacting genes: ADAM33 AGR3 CLDN11 CLEC7A FAM3C HGFAC HMGB1 KRTAP1-3 MAL NLGN3 SLC38A7 SMCO4 ST14 TENT5A TF TMEM109 TMEM190 TMEM97 TSPAN33 UBQLN2 UBQLN4 UPK1B VAMP5
Entrez ID		6692
HPRD ID		05494
Ensembl ID		ENSG00000166145
Uniprot IDs		O43278
PDB IDs		1YC0 2MSX 4ISL 4ISN 4ISO 5EZD 5H7V
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Wound Healing Cell Surface Positive Regulation Of Monocyte Chemotactic Protein-1 Production Basal Part Of Cell
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