SMS

Description		spermine synthase
Image
GO Annotations	Cellular Component	Cytosol Extracellular Exosome
	Molecular Function	Transferase Activity Spermine Synthase Activity
	Biological Process	Methionine Metabolic Process Polyamine Metabolic Process Polyamine Biosynthetic Process Spermine Biosynthetic Process Spermine Metabolic Process
Pathways		Metabolism of polyamines
Drugs		Spermine
Diseases		Snyder-Robinson syndrome
GWAS
Novel Interacting Genes		1 novel interacting genes: LARP7
Interacting Genes		6 interacting genes: CEBPA EZH2 MAPK6 MAPK8IP2 MAPKAPK3 RPS6KA3
Entrez ID		6611
HPRD ID		02115
Ensembl ID		ENSG00000102172
Uniprot IDs		P52788
PDB IDs		3C6K 3C6M
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Transcription Elongation By RNA Polymerase II Intracellular Signaling Cassette Response To Lipid Intracellular Signal Transduction Animal Organ Regeneration MAPK Cascade Toll-like Receptor Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Hepatocyte Homeostasis Protein Serine/threonine Kinase Activity Protein Serine Kinase Activity U6 2'-O-snRNA Methylation Nucleoplasm Chromatin DNA Binding Response To Vitamin B2 Positive Regulation Of Defense Response Liver Development C/EBP Complex Cellular Response To Trichostatin A Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Septin Cytoskeleton Protein Kinase Binding Protein Kinase Activity CHOP-C/EBP Complex Positive Regulation Of Developmental Process Regeneration Histone H3K27 Trimethyltransferase Activity Response To Tetrachloromethane Box C/D Sno(s)RNA 3'-end Processing Kinase Activity White Fat Cell Proliferation Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Positive Regulation Of SnRNA Transcription By RNA Polymerase II 7SK SnRNP Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Histone H3K27 Methyltransferase Activity Innate Immune Response-activating Signaling Pathway Ribosomal Protein S6 Kinase Activity Calcium-dependent Protein Serine/threonine Kinase Activity SnRNA Modification Response To Phenylpropanoid Protein-containing Complex Pronucleus Negative Regulation Of Retinoic Acid Receptor Signaling Pathway Transferase Activity Methylation
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