SLC22A2

Gene Name		solute carrier family 22 (organic cation transporter), member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Steroid Binding Organic Cation Transmembrane Transporter Activity Choline Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity
	Biological Process	Drug Transmembrane Transport Synaptic Transmission Neurotransmitter Secretion Body Fluid Secretion Organic Cation Transport Quaternary Ammonium Group Transport Choline Transport Ion Transmembrane Transport Neurotransmitter Biosynthetic Process Small Molecule Metabolic Process Histamine Transport Transmembrane Transport
Pathways		Na+/Cl- dependent neurotransmitter transporters Neurotransmitter Release Cycle Neurotransmitter Clearance In The Synaptic Cleft Organic cation transport Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Norepinephrine Neurotransmitter Release Cycle Abacavir transmembrane transport Organic cation/anion/zwitterion transport SLC-mediated transmembrane transport Abacavir transport and metabolism Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Creatinine levels ( 20383145)
Protein-protein Interactions		9 interactors: AGO3 CST9L ETV5 EXT2 GTF2B HYAL3 LSM4 POU2AF1 SUMO2
Entrez ID		6582
HPRD ID		04008
Ensembl ID		ENSG00000112499
Uniprot IDs		O15244
PDB IDs
Enriched GO Terms of Interacting Partners?		Nitrogen Compound Metabolic Process Heparan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process MRNA Catabolic Process Male Germ-line Stem Cell Asymmetric Division Glycosaminoglycan Metabolic Process RNA Catabolic Process Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Cellular Response To UV-B Skeletal Muscle Acetylcholine-gated Channel Clustering RNA Metabolic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Translation Involved In Gene Silencing By MiRNA
Tagcloud ?		4alpha ahn brush cyp2d2 cyp2d4 dme dmes fmo1 ggt1 handled hnf1a hnf4a massively mate1 metabolizing nfe2l2 nigam nqo2 nr3c1 oat1 oat3 oct1 oct2 pt slc47a1 wu