CXCR5

Gene Name		chemokine (C-X-C motif) receptor 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	G-protein Coupled Receptor Activity Protein Binding C-X-C Chemokine Receptor Activity
	Biological Process	Movement Of Cell Or Subcellular Component Chemotaxis Immune Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytokinesis B Cell Activation Lymph Node Development Chemokine-mediated Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 21833088) Primary biliary cirrhosis ( 21399635) Vitiligo ( 22951725)
Protein-protein Interactions		1 interactors: CXCL13
Entrez ID		643
HPRD ID		03367
Ensembl ID
Uniprot IDs		A0N0R2 A8K647 P32302 Q2YD84
PDB IDs
Enriched GO Terms of Interacting Partners?		Endothelial Cell Chemotaxis To Fibroblast Growth Factor B Cell Chemotaxis Across High Endothelial Venule Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Lymphocyte Chemotaxis Across High Endothelial Venule Activation Of Rap GTPase Activity B Cell Chemotaxis Negative Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Integrin Activation Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of T Cell Chemotaxis Regulation Of Integrin Activation Chronic Inflammatory Response Endothelial Cell Chemotaxis Germinal Center Formation Lymphocyte Chemotaxis Lymph Node Development Positive Regulation Of Rap GTPase Activity Positive Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of T Cell Migration Regulation Of T Cell Migration Regulation Of Rap GTPase Activity Regulation Of Rap Protein Signal Transduction Negative Regulation Of Chemotaxis Lymphocyte Migration Regulation Of Lymphocyte Migration Negative Regulation Of Endothelial Cell Migration Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Receptor Activity Negative Regulation Of Epithelial Cell Migration Regulation Of Humoral Immune Response Activation Of Ras GTPase Activity Chemokine-mediated Signaling Pathway Positive Regulation Of Leukocyte Chemotaxis Endothelial Cell Migration Positive Regulation Of Leukocyte Migration Epithelial Cell Migration Epithelium Migration Leukocyte Chemotaxis Regulation Of Endothelial Cell Migration Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Chemotaxis Regulation Of Leukocyte Migration Regulation Of Receptor Activity Positive Regulation Of Behavior Regulation Of Chemotaxis Regulation Of Epithelial Cell Migration Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Chemotaxis
Tagcloud ?		account acute alterations asthma bcl blimp cd4 circulating classified cytometry detect elisa enrolled follicular helper ige il immunological lymphocytes microenvironment mrna negatively plasma positively proportion remission sandwich sixty tfh