FIGNL1

Gene Name		fidgetin-like 1
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome Nucleus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Protein Binding ATP Binding Microtubule-severing ATPase Activity Hydrolase Activity
	Biological Process	Osteoblast Differentiation Regulation Of Double-strand Break Repair Via Homologous Recombination Cytoplasmic Microtubule Organization Osteoblast Proliferation Negative Regulation Of Apoptotic Process ATP Metabolic Process Regulation Of Cell Cycle Cellular Response To Ionizing Radiation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 21102463)
Protein-protein Interactions		2 interactors: ITGB1BP1 KDM1A
Entrez ID		63979
HPRD ID		10958
Ensembl ID		ENSG00000132436
Uniprot IDs		Q6PIW4
PDB IDs		3D8B
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Binding Negative Regulation Of Binding Regulation Of Protein Binding Regulation Of Primitive Erythrocyte Differentiation Regulation Of Binding Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Targeting To Membrane Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Integrin Activation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Negative Regulation Of Fibroblast Migration Myoblast Migration Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Histone H3-K4 Demethylation Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Cell Proliferation Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Focal Adhesion Assembly Positive Regulation Of Cell Proliferation Regulation Of Cell Migration Involved In Sprouting Angiogenesis Granulocyte Differentiation Regulation Of Sprouting Angiogenesis Endothelial Cell Proliferation Negative Regulation Of Protein Metabolic Process Regulation Of Organelle Organization Regulation Of Megakaryocyte Differentiation Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Histone Methylation Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Adherens Junction Organization Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Signal Transduction Regulation Of Hormone Biosynthetic Process Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Notch Signaling Pathway Regulation Of Cdc42 GTPase Activity Positive Regulation Of Protein Targeting To Membrane
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