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PKNOX2

Gene Name PBX/knotted 1 homeobox 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Actin Cytoskeleton
  • Microtubule Cytoskeleton
Molecular Function
  • DNA Binding
  • Actin Monomer Binding
  • Sequence-specific DNA Binding
  • Actin Filament Binding
Biological Process
  • Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS
  • Alcohol and nictotine co-dependence ( 22488850)
  • Alcohol dependence ( 21956439 21703634)
  • Formal thought disorder in schizophrenia ( 22648509)
  • Obesity-related traits ( 23251661)
  • Schizophrenia ( 22688191)
  • Substance dependence ( 21298047)
Protein-protein Interactions 1 interactors: HOXB1
Entrez ID 63876
HPRD ID 17857
Ensembl ID ENSG00000165495
Uniprot IDs B7ZAF3 Q96KN3
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Facial Nucleus Development
  • Rhombomere 4 Development
  • Rhombomere 5 Development
  • Rhombomere Development
  • Facial Nerve Structural Organization
  • Pons Development
  • Facial Nerve Morphogenesis
  • Parasympathetic Nervous System Development
  • Anatomical Structure Arrangement
  • Autonomic Nervous System Development
  • Neural Nucleus Development
  • Cranial Nerve Development
  • Nerve Development
  • Embryonic Skeletal System Morphogenesis
  • Metencephalon Development
  • Embryonic Skeletal System Development
  • Hindbrain Development
  • Anterior/posterior Pattern Specification
  • Skeletal System Morphogenesis
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