CCL22

Name	C-C motif chemokine ligand 22
Structure	No pdb structure
Novel Interactors	1 novel interactors: NLGN4X
Interactors	10 interactors: AQP6 CCL14 CCL19 CCR4 CRYAB DPP4 GCLC HERC3 PF4V1 VCAM1
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Response To Virus Positive Regulation Of Cell Migration Killing Of Cells Of Another Organism Eosinophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways	Chemokine receptors bind chemokines Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling
GWAS	Asthma ( 32296059 ) Blood protein levels ( 30072576 ) Multiple sclerosis ( 24076602 ) Systemic lupus erythematosus ( 28714469 33272962 )
Entrez ID	6367
HPRD ID	04263
Ensembl ID	ENSG00000102962
Uniprot IDs	O00626
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Chemotaxis Locomotion Cell Chemotaxis Chemokine Activity Cell Migration Inflammatory Response Chemokine-mediated Signaling Pathway Cell Motility Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Defense Response Response To Stress Antimicrobial Humoral Response CCR Chemokine Receptor Binding Regulation Of Neutrophil Chemotaxis Cytokine Activity Regulation Of Neutrophil Migration T Cell Costimulation Nitrate Transmembrane Transporter Activity Immune System Process Cell Surface Positive Regulation Of T Cell Activation Regulation Of Granulocyte Chemotaxis Glucagon Processing Regulation Of Cell Activation Humoral Immune Response Positive Regulation Of Dendritic Cell Dendrite Assembly Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex Cardiac Neuron Differentiation Positive Regulation Of Leukocyte Cell-cell Adhesion Response To Hypoxia PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Extracellular Region Response To Lipid Response To Oxygen Levels Response To Decreased Oxygen Levels Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Cellular Response To Thyroxine Stimulus Negative Regulation Of Hepatic Stellate Cell Activation Glutamate-cysteine Ligase Activity Glutamate-cysteine Ligase Complex Granulocyte Chemotaxis CCR7 Chemokine Receptor Binding CCL19-activated CCR7 Signaling Pathway Peripheral Nervous System Neuron Differentiation Response To Heat Granulocyte Migration Cell Adhesion Molecule Binding Regulation Of Leukocyte Cell-cell Adhesion