SERPINB3

Gene Name		serpin peptidase inhibitor, clade B (ovalbumin), member 3
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Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Vesicle Extracellular Vesicular Exosome
	Molecular Function	Virus Receptor Activity Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Response To Virus Negative Regulation Of Peptidase Activity Negative Regulation Of Endopeptidase Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Proteolysis
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: CTSK CTSL CTSS MAPK8 UCHL5
Entrez ID		6317
HPRD ID		02745
Ensembl ID		ENSG00000057149
Uniprot IDs		P29508
PDB IDs		2ZV6
Enriched GO Terms of Interacting Partners?		Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Regulation Of Innate Immune Response Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Immune Response-regulating Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Response To Thyroid Hormone Stimulus Protein Catabolic Process Positive Regulation Of Immune Response Response To Thyroid Hormone Innate Immune Response Cellular Macromolecule Catabolic Process Regulation Of Immune Response Positive Regulation Of Immune System Process Extracellular Matrix Organization Extracellular Structure Organization Immune Response Regulation Of Immune System Process Defense Response Response To Stress Proteolysis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Catabolic Process Cellular Response To Organic Substance Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Cellular Protein Metabolic Process Immune System Process Basement Membrane Disassembly Macrophage Apoptotic Process Signal Transduction Response To Organic Substance Protein Metabolic Process Signaling Cell Communication Antigen Processing And Presentation Of Peptide Antigen JUN Phosphorylation Positive Regulation Of Deacetylase Activity Adaptive Immune Response Ossification Antigen Processing And Presentation Myeloid Cell Apoptotic Process
Tagcloud ?		autocrine contributes contributions cysteine emt halted il6 makes malignancy mammary mechanistically mesenchymal neu nonlethal oncogenic phenotypes prolonged promoted promotes promoting protease protumorigenic scca1 sufficient tumorigenesis unfolded upr upregulated