RTKN

Description		rhotekin
Image		No pdb structure
GO Annotations	Cellular Component	Actomyosin Contractile Ring Cytosol
	Molecular Function	Nucleotide Binding GTPase Inhibitor Activity Protein Binding GTP Binding Small GTPase Binding
	Biological Process	Mitotic Cytokinesis Actomyosin Contractile Ring Assembly Apoptotic Process Signal Transduction Rho Protein Signal Transduction Septin Ring Organization Regulation Of Apoptotic Process
Pathways		RHO GTPases Activate Rhotekin and Rhophilins RHO GTPases Activate Rhotekin and Rhophilins RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		12 interacting genes: AKAP13 APP GOPC MAP1LC3A MFHAS1 RAC2 RHOA RHOB RHOC SMURF1 TAX1BP3 TGFBR1
Entrez ID		6242
HPRD ID		03795
Ensembl ID		ENSG00000114993
Uniprot IDs		A0A1W2PPZ2 Q9BST9
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Intracellular Signaling Cassette Small GTPase-mediated Signal Transduction Skeletal Muscle Satellite Cell Migration Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Signal Transduction Regulation Of Actin Cytoskeleton Organization GTP Binding Regulation Of Supramolecular Fiber Organization Regulation Of Actin Filament-based Process Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Stress Fiber Assembly Cleavage Furrow Negative Regulation Of Protein Localization Supramolecular Fiber Organization Rho Protein Signal Transduction Positive Regulation Of Lipase Activity Positive Regulation Of Actin Filament Bundle Assembly Mitotic Cytokinesis Apical Junction Assembly Regulation Of Cytoskeleton Organization Regulation Of Cell Migration Actin Filament Organization Endothelial Tube Morphogenesis Negative Regulation Of Protein Localization To Cell Surface Regulation Of Cell Motility Cytoskeleton-dependent Cytokinesis Regulation Of Stress Fiber Assembly Regulation Of Locomotion Positive Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Intracellular Signal Transduction Regulation Of Modification Of Postsynaptic Structure GTPase Activity I-SMAD Binding Regulation Of Cell Projection Organization Response To Lead Ion Regulation Of Modification Of Synaptic Structure Regulation Of Reactive Oxygen Species Metabolic Process Cellular Response To Copper Ion Positive Regulation Of Leukocyte Migration Regulation Of Intracellular Signal Transduction Extracellular Exosome Negative Regulation Of Signal Transduction Wound Healing, Spreading Of Cells Regulation Of Signal Transduction Regulation Of Protein Localization
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