REV3L

Gene Name		REV3-like, polymerase (DNA directed), zeta, catalytic subunit
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Zeta DNA Polymerase Complex
	Molecular Function	Nucleotide Binding DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	DNA-dependent DNA Replication DNA Repair Error-prone Translesion Synthesis
Pathways		Translesion synthesis by Pol zeta DNA Damage Bypass Translesion synthesis by DNA polymerases bypassing lesion on DNA template
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-protein Interactions		5 interactors: CHEK2 HDAC4 MAD2L1 MAD2L2 REV1
Entrez ID		5980
HPRD ID		04145
Ensembl ID		ENSG00000009413
Uniprot IDs		O60673
PDB IDs		3ABD 3ABE 3VU7 4EXT 4GK0 4GK5
Enriched GO Terms of Interacting Partners?		Negative Regulation Of APC-Cdc20 Complex Activity Mitotic Cell Cycle Checkpoint Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Regulation Of Cell Cycle Phase Transition Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Nuclear Division Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Protein Catabolic Process Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cell Division Negative Regulation Of Cell Cycle Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Signal Transduction In Response To DNA Damage DNA Repair Negative Regulation Of Protein Ubiquitination Signal Transduction Involved In Intra-S DNA Damage Checkpoint Mitotic Cell Cycle Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Negative Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Double-strand Break Repair Cellular Response To DNA Damage Stimulus Regulation Of Cell Cycle Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Ubiquitination Regulation Of Chromosome Organization Cell Cycle Process Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin
Tagcloud ?		adriamycin cgi cgis cox7a2l cpg damaging deal distinctly enrichment hct116 hnrpul1 island jag2 mildly pcna peroxidase phenomena repressed scenarios scfd2 stabilize stabilized stresses syvn1 tor1aip1 unchanged varies verified xpmc2h