HRH4

Gene Name		histamine receptor H4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Histamine Receptor Activity
	Biological Process	Inflammatory Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Biological_process Regulation Of MAPK Cascade
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Histamine receptors
Drugs		Clozapine Histamine Phosphate
Diseases
GWAS		Response to taxane treatment (docetaxel) ( 23006423)
Protein-protein Interactions		4 interactors: CCL16 GNA15 GNAI1 GNAO1
Entrez ID		59340
HPRD ID		06004
Ensembl ID		ENSG00000134489
Uniprot IDs		B2KJ49 Q9H3N8
PDB IDs
Enriched GO Terms of Interacting Partners?		Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Dopamine Receptor Signaling Pathway Platelet Activation G-protein Coupled Receptor Signaling Pathway Response To Stress Phospholipase C-activating G-protein Coupled Acetylcholine Receptor Signaling Pathway Phospholipase C-activating Dopamine Receptor Signaling Pathway Blood Coagulation Hemostasis G-protein Coupled Acetylcholine Receptor Signaling Pathway Signaling Regulation Of Body Fluid Levels Cell Communication Wound Healing Positive Chemotaxis Cell Activation Response To Wounding Cellular Response To Stimulus Response To Morphine Negative Regulation Of Calcium Ion Transport Response To Organonitrogen Compound Cell Surface Receptor Signaling Pathway Cell-cell Signaling Activation Of Phospholipase C Activity Vesicle Fusion Positive Regulation Of Phospholipase C Activity Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Hydrolase Activity Organelle Fusion Positive Regulation Of Phospholipase Activity Response To Stimulus Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Response To Ammonium Ion Negative Regulation Of Ion Transport
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