PTX3

Description		pentraxin 3
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Specific Granule Lumen Tertiary Granule Lumen
	Molecular Function	Complement Component C1q Complex Binding (1->3)-beta-D-glucan Binding Protein Binding Identical Protein Binding Virion Binding
	Biological Process	Ovarian Cumulus Expansion Response To Yeast Immune System Process Inflammatory Response Immune Response Opsonization Extracellular Matrix Organization Host-mediated Suppression Of Viral Proces Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Innate Immune Response Positive Regulation Of Nitric Oxide Biosynthetic Process Host-mediated Suppression Of Symbiont Invasion Positive Regulation Of Phagocytosis Response To Other Organism Negative Regulation Of Glycoprotein Metabolic Process
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		16 interacting genes: C1QA C1QB C1QC CFH FGF1 FGF16 FGF17 FGF18 FGF2 FGF20 FGF22 FGF5 FGF7 FGF8 MTNR1A SNCA
Entrez ID		5806
HPRD ID		03928
Ensembl ID		ENSG00000163661
Uniprot IDs		P26022
PDB IDs		7ZL1 8PVQ 8S50
Enriched GO Terms of Interacting Partners?		Fibroblast Growth Factor Receptor Signaling Pathway Neurogenesis Growth Factor Activity Fibroblast Growth Factor Receptor Binding Extracellular Region Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of MAPK Cascade Type 2 Fibroblast Growth Factor Receptor Binding Extracellular Space Cell-cell Signaling Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Signaling Enzyme-linked Receptor Protein Signaling Pathway Cell Communication Regulation Of MAPK Cascade Regulation Of Locomotion Complement Component C1q Complex Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Positive Regulation Of Cell Population Proliferation Symbiont Cell Surface Regulation Of Cell Migration Regulation Of Cell Motility IgM Binding Complement Component C1 Complex Positive Regulation Of Intracellular Signal Transduction Type 1 Fibroblast Growth Factor Receptor Binding Positive Regulation Of Cell Division Lung Development Postsynapse Positive Regulation Of Cell Communication Positive Regulation Of Signaling Synapse Pruning Complement Activation Regulation Of Sprouting Angiogenesis IgG Binding Positive Regulation Of Signal Transduction Positive Regulation Of Endothelial Cell Chemotaxis Regulation Of Cell Population Proliferation Regulation Of MAP Kinase Activity Regulation Of Cell Division Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Animal Organ Morphogenesis Organ Induction Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Animal Organ Formation Corticotropin Hormone Secreting Cell Differentiation Developmental Induction Chemoattractant Activity Positive Regulation Of Endothelial Cell Migration
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