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VANGL2
Gene Name
VANGL planar cell polarity protein 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Stress Fiber
Plasma Membrane
Cell-cell Junction
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Lateral Plasma Membrane
ER To Golgi Transport Vesicle
Cell Pole
Molecular Function
Biological Process
Establishment Of Planar Polarity
Neural Tube Closure
Hair Follicle Development
Heart Looping
Membranous Septum Morphogenesis
Muscular Septum Morphogenesis
Planar Cell Polarity Pathway Involved In Axis Elongation
Rho Protein Signal Transduction
Anterior/posterior Pattern Specification
Convergent Extension Involved In Neural Plate Elongation
Regulation Of Wnt Signaling Pathway
Glomerulus Development
Regulation Of Actin Cytoskeleton Organization
Somatic Stem Cell Maintenance
Nonmotile Primary Cilium Assembly
Cell Migration Involved In Kidney Development
Post-anal Tail Morphogenesis
Wound Healing
Positive Regulation Of JUN Kinase Activity
Apical Protein Localization
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Somatic Stem Cell Division
Establishment Of Body Hair Planar Orientation
Digestive Tract Morphogenesis
Convergent Extension Involved In Axis Elongation
Inner Ear Receptor Stereocilium Organization
Orthogonal Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis
Planar Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis
Lateral Sprouting Involved In Lung Morphogenesis
Kidney Morphogenesis
Planar Cell Polarity Pathway Involved In Heart Morphogenesis
Cochlea Morphogenesis
Establishment Of Planar Polarity Involved In Neural Tube Closure
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Pathways
Asymmetric localization of PCP proteins
Signaling by Wnt
PCP/CE pathway
beta-catenin independent WNT signaling
Drugs
Diseases
GWAS
Cognitive performance (
19734545
)
Protein-protein Interactions
2 interactors:
DVL1
MAGI3
Entrez ID
57216
HPRD ID
02758
Ensembl ID
ENSG00000162738
Uniprot IDs
A8K4L6
Q9ULK5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Convergent Extension Involved In Neural Plate Elongation
Collateral Sprouting
Convergent Extension Involved In Organogenesis
Protein Localization To Microtubule
Neural Plate Morphogenesis
Skeletal Muscle Acetylcholine-gated Channel Clustering
Regulation Of Protein Kinase Activity
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Regulation Of Kinase Activity
Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure
Convergent Extension
Prepulse Inhibition
Neural Plate Development
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Protein Localization To Cytoskeleton
Regulation Of Protein Phosphorylation
Cochlea Morphogenesis
Startle Response
Positive Regulation Of Cellular Protein Metabolic Process
Postsynaptic Membrane Organization
Non-canonical Wnt Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Signal Transduction
Regulation Of Phosphorylation
Cytoplasmic Microtubule Organization
Social Behavior
Axon Extension
Regulation Of Phosphorus Metabolic Process
Cochlea Development
Receptor Clustering
Neuromuscular Junction Development
Negative Regulation Of Protein Binding
Nucleotide Phosphorylation
Morphogenesis Of An Epithelial Sheet
Neuron Projection Extension
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of JUN Kinase Activity
Intracellular Signal Transduction
Dendrite Morphogenesis
Regulation Of JUN Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Developmental Cell Growth
Canonical Wnt Signaling Pathway
Negative Regulation Of Binding
Inner Ear Morphogenesis
Regulation Of Protein Metabolic Process
Neurotransmitter Secretion
Regulation Of Embryonic Development
Positive Regulation Of Canonical Wnt Signaling Pathway
Tagcloud
?
adds
arealization
axon
axons
barrel
celsr2
celsr3
conditional
contexts
forebrain
fzd3
guidance
guidepost
inactivation
mimics
navigation
pcp
perturbs
planar
polarity
projections
redundantly
thalamic
thalamocortical
thalamus
unexpectedly
wiring