VARS2

Gene Name		valyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol
	Molecular Function	Aminoacyl-tRNA Editing Activity Valine-tRNA Ligase Activity ATP Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Valyl-tRNA Aminoacylation Regulation Of Translational Fidelity Gene Expression
Pathways		tRNA Aminoacylation Mitochondrial tRNA aminoacylation
Drugs
Diseases
GWAS		HIV-1 control ( 20041166) Pubertal anthropometrics ( 23449627) Ulcerative colitis ( 20848476)
Protein-protein Interactions		6 interactors: ABI2 CMTM5 MAL2 NCK2 PIK3CA SORBS3
Entrez ID		57176
HPRD ID		11670
Ensembl ID		ENSG00000137411
Uniprot IDs		B4E0K6 Q5ST30
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cytoskeleton Organization Actin Filament Organization Regulation Of Actin Cytoskeleton Organization Locomotion Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Regulation Of Cytoskeleton Organization Actin Cytoskeleton Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Actin Filament-based Process Regulation Of Peptidyl-serine Phosphorylation Hypomethylation Of CpG Island Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Cell Migration Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Motility Regulation Of Organelle Organization Positive Regulation Of T Cell Activation Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Positive Regulation Of Homotypic Cell-cell Adhesion Muscle Contraction Cytoskeleton Organization Positive Regulation Of Cell-cell Adhesion Regulation Of Genetic Imprinting Muscle System Process Regulation Of T Cell Activation Regulation Of Phosphorylation Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Cell Activation Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Actin Nucleation Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Negative Regulation Of Fibroblast Apoptotic Process Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Cellular Amino Acid Metabolic Process Signal Complex Assembly Negative Regulation Of Anoikis Regulation Of Cell Activation Regulation Of Anoikis Regulation Of DNA Methylation Regulation Of Cellular Ketone Metabolic Process Rac Protein Signal Transduction Regulation Of Fibroblast Apoptotic Process Regulation Of Arp2/3 Complex-mediated Actin Nucleation Phosphatidylinositol-3-phosphate Biosynthetic Process Regulation Of Cellular Component Organization
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