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STRADB
Description
STE20 related adaptor beta
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Aggresome
Serine/threonine Protein Kinase Complex
Molecular Function
Nucleotide Binding
Protein Kinase Activity
Protein Binding
ATP Binding
Protein Serine/threonine Kinase Activator Activity
Biological Process
Cell Morphogenesis
Protein Phosphorylation
Protein Export From Nucleus
JNK Cascade
Activation Of Protein Kinase Activity
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Energy dependent regulation of mTOR by LKB1-AMPK
Drugs
Diseases
GWAS
Novel Interacting Genes
3 novel interacting genes:
COQ10B
PPIL3
SF3B1
Interacting Genes
8 interacting genes:
CAB39
GRB2
MAP3K7
NEB
STK11
TRAF6
UBC
XIAP
Entrez ID
55437
HPRD ID
09546
Ensembl ID
ENSG00000082146
Uniprot IDs
Q9C0K7
PDB IDs
Enriched GO Terms of Interacting Partners
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Protein Serine/threonine Kinase Binding
Immune Response-activating Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
Immune Response-regulating Signaling Pathway
Activation Of Immune Response
Canonical NF-kappaB Signal Transduction
Interleukin-17A-mediated Signaling Pathway
Interleukin-33-mediated Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Type I Interferon Production
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Anoikis
Positive Regulation Of JUN Kinase Activity
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Immune Response
Negative Regulation Of Canonical NF-kappaB Signal Transduction
Cytoplasmic Pattern Recognition Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
T Cell Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Positive Regulation Of Protein Modification Process
DNA Damage Response
Regulation Of Type I Interferon Production
Positive Regulation Of Kinase Activity
Positive Regulation Of Protein Kinase Activity
Serine/threonine Protein Kinase Complex
Stimulatory C-type Lectin Receptor Signaling Pathway
Cellular Response To Lectin
Fc-epsilon Receptor Signaling Pathway
P38MAPK Cascade
Regulation Of Innate Immune Response
Interleukin-1-mediated Signaling Pathway
Endolysosomal Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Positive Regulation Of T Cell Cytokine Production
Innate Immune Response-activating Signaling Pathway
Regulation Of Immune Response
Cellular Response To Stress
Non-canonical NF-kappaB Signal Transduction
Regulation Of Lymphocyte Mediated Immunity
Positive Regulation Of MAP Kinase Activity
Positive Regulation Of Immune System Process
Positive Regulation Of Interleukin-2 Production
Activation Of Innate Immune Response
Activation Of Protein Kinase Activity
Regulation Of T Cell Cytokine Production
Protein Kinase Activator Activity
Toll-like Receptor 4 Signaling Pathway
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