HJURP

Gene Name		Holliday junction recognition protein
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Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome Kinetochore Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	DNA Binding Protein Binding Histone Binding Identical Protein Binding
	Biological Process	Nucleosome Assembly Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Regulation Of Protein Complex Assembly Regulation Of DNA Binding
Pathways		Chromosome Maintenance Nucleosome assembly Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: HIST1H4A IMMT STT3A
Entrez ID		55355
HPRD ID		10912
Ensembl ID		ENSG00000123485
Uniprot IDs		Q8NCD3
PDB IDs		3R45
Enriched GO Terms of Interacting Partners?		Co-translational Protein Modification Histone H4-K20 Demethylation Negative Regulation Of Megakaryocyte Differentiation DNA Replication-dependent Nucleosome Assembly Negative Regulation Of Hematopoietic Progenitor Cell Differentiation DNA Methylation On Cytosine Chromatin Silencing At RDNA Mitochondrial Calcium Ion Homeostasis Regulation Of Megakaryocyte Differentiation CENP-A Containing Nucleosome Assembly Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Exchange Chromatin Silencing DNA Replication-independent Nucleosome Assembly Histone Lysine Demethylation Histone Demethylation Protein Demethylation Centromere Complex Assembly Response To Cold DNA Methylation Demethylation ATP-dependent Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic Homeostatic Process Telomere Maintenance Negative Regulation Of Myeloid Cell Differentiation DNA Modification Protein N-linked Glycosylation Via Asparagine Gene Silencing
Tagcloud ?		assembly cdk1 cenp centromere centromeres centromeric dephosphorylation deposition dynamic eliminates exit favor identity loading making minimum mitosis mitotic newly orchestrates pp1alpha precise premature preventing propagation ser68 spatiotemporal synthesized variant