LIN7C

Gene Name		lin-7 homolog C (C. elegans)
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Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell-cell Junction Tight Junction Postsynaptic Density Basolateral Plasma Membrane Neuron Projection Synapse Postsynaptic Membrane Extracellular Vesicular Exosome MPP7-DLG1-LIN7 Complex
	Molecular Function	Cytoskeletal Protein Binding Protein Domain Specific Binding PDZ Domain Binding L27 Domain Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Exocytosis Neurotransmitter Secretion Asymmetric Protein Localization Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Bone mineral density ( 22504420)
Protein-protein Interactions		4 interactors: ABCA1 BAIAP2 HTR2C KCNJ12
Entrez ID		55327
HPRD ID		17279
Ensembl ID		ENSG00000148943
Uniprot IDs		Q9NUP9
PDB IDs		3LRA
Enriched GO Terms of Interacting Partners?		Phospholipase C-activating Serotonin Receptor Signaling Pathway Regulation Of Corticotropin-releasing Hormone Secretion Positive Regulation Of Phosphatidylinositol Biosynthetic Process Interleukin-1 Beta Secretion Phagocytosis Apolipoprotein A-I-mediated Signaling Pathway Positive Regulation Of Phospholipid Biosynthetic Process Interleukin-1 Secretion Negative Regulation Of Cholesterol Storage High-density Lipoprotein Particle Assembly Intracellular Cholesterol Transport Intracellular Sterol Transport Phospholipid Homeostasis Ion Transport Platelet Dense Granule Organization Response To External Stimulus Endomembrane System Organization Cellular Component Assembly Response To Nutrient Levels Phospholipid Efflux Phagocytosis, Engulfment Transport Response To Low-density Lipoprotein Particle Interleukin-1 Beta Production Response To Extracellular Stimulus Response To Bacterium Serotonin Receptor Signaling Pathway Cellular Response To Cholesterol Negative Regulation Of Macrophage Derived Foam Cell Differentiation Response To Drug Reverse Cholesterol Transport Response To Laminar Fluid Shear Stress Membrane Invagination Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Actin Crosslink Formation Protein-lipid Complex Assembly Response To Lipoprotein Particle Cellular Response To Sterol Positive Regulation Of Cholesterol Efflux Negative Regulation Of Lipid Storage Signaling Ion Homeostasis Positive Regulation Of Cholesterol Transport CGMP Biosynthetic Process Cell Communication Synaptic Transmission Regulation Of Appetite Regulation Of Cholesterol Efflux Response To Cholesterol Potassium Ion Import
Tagcloud ?		adiposity alleles bcdin3d bdnf bmi chinese circumference dgkg etv5 europeans faim2 former fto gnpda2 hong kctd15 kong loci lost mc4r modestly mtch2 negr1 obesity sec16b sh2b1 t2d tmem18 waist