RNF125

Gene Name		ring finger protein 125, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Protein Ubiquitination Negative Regulation Of Type I Interferon Production Innate Immune Response
Pathways		RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Negative regulators of RIG-I/MDA5 signaling Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		17 interactors: CHFR PCGF1 PML TRIM46 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E2 UBE2K UBE2L3 UBE2L6 UBE2N UBE2U UBE2W USP2
Entrez ID		54941
HPRD ID		11500
Ensembl ID		ENSG00000101695
Uniprot IDs		Q96EQ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Modification Process Protein K48-linked Ubiquitination Proteolysis Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Protein Metabolic Process Protein K11-linked Ubiquitination Proteasomal Protein Catabolic Process Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Toll-like Receptor 4 Signaling Pathway Cellular Response To Stress Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Mitotic Cell Cycle Regulation Of Protein Ubiquitination Regulation Of Ubiquitin-protein Transferase Activity Innate Immune Response Regulation Of Innate Immune Response Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To DNA Damage Stimulus Cellular Response To Oxygen Levels Response To Hypoxia Response To Stress Protein K63-linked Ubiquitination Cellular Metabolic Process Histone Ubiquitination Positive Regulation Of Protein Ubiquitination Transforming Growth Factor Beta Receptor Signaling Pathway Protein Monoubiquitination
Tagcloud ?		75a ag aims basel blotting c72 degradation e3 exogenous gst immunoprecipitation interacted interfere interference ip karger ligase mdm2 negatively p53 physically proteasome pull repressed thought transactivation ubiquitin ubiquitinated ubiquitination