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SLX1A
Gene Name
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Slx1-Slx4 Complex
Molecular Function
Protein Binding
Crossover Junction Endodeoxyribonuclease Activity
5'-flap Endonuclease Activity
Metal Ion Binding
Biological Process
Double-strand Break Repair Via Homologous Recombination
DNA Catabolic Process, Endonucleolytic
DNA Repair
DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
6 interactors:
EME1
ERCC1
ERCC4
GRB2
MUS81
SLX4
Entrez ID
548593
HPRD ID
18681
Ensembl ID
ENSG00000132207
Uniprot IDs
Q9BQ83
PDB IDs
Enriched GO Terms of Interacting Partners
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Response To Intra-S DNA Damage Checkpoint Signaling
DNA Recombination
Cellular Response To DNA Damage Stimulus
Nucleic Acid Phosphodiester Bond Hydrolysis
DNA Catabolic Process, Endonucleolytic
DNA Catabolic Process
DNA Repair
Cellular Response To Stress
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Nucleotide-excision Repair, DNA Incision, 3'-to Lesion
Nucleotide-excision Repair, DNA Incision
DNA Metabolic Process
Nucleotide-excision Repair
Interstrand Cross-link Repair
Aromatic Compound Catabolic Process
Negative Regulation Of Telomere Maintenance
UV Protection
Double-strand Break Repair
Nucleotide-excision Repair, DNA Damage Removal
Regulation Of Telomere Maintenance
Response To Stress
Cellular Macromolecule Catabolic Process
Transcription-coupled Nucleotide-excision Repair
Response To Radiation
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Negative Regulation Of Chromosome Organization
Negative Regulation Of DNA Metabolic Process
Nucleotide-excision Repair Involved In Interstrand Cross-link Repair
Catabolic Process
Response To UV
Cellular Response To Stimulus
Response To Ionizing Radiation
Response To Biotic Stimulus
Post-embryonic Hemopoiesis
DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing
Telomere Maintenance Via Telomere Shortening
Pyrimidine Dimer Repair By Nucleotide-excision Repair
Regulation Of Organelle Organization
Regulation Of Chromosome Organization
Nucleobase-containing Compound Metabolic Process
Replicative Cell Aging
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Response To Stimulus
Response To Abiotic Stimulus
DNA Double-strand Break Processing
Cellular Nitrogen Compound Metabolic Process
Branching Involved In Labyrinthine Layer Morphogenesis
Aging
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