GATAD2A

Gene Name		GATA zinc finger domain containing 2A
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm NuRD Complex Nuclear Speck
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Binding, Bridging Sequence-specific DNA Binding
	Biological Process	Blood Vessel Development In Utero Embryonic Development Neural Fold Formation DNA Methylation Transcription, DNA-templated Embryonic Body Morphogenesis Programmed Cell Death Anterior Neuropore Closure Negative Regulation Of Transcription, DNA-templated
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: HDAC1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE KAT2B KRT40 MBD2 MBD3 PAK4
Entrez ID		54815
HPRD ID		11741
Ensembl ID		ENSG00000167491
Uniprot IDs		Q86YP4
PDB IDs		2L2L
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Chromatin Organization Chromatin Remodeling Regulation Of Gene Expression, Epigenetic ATP-dependent Chromatin Remodeling Chromosome Organization Chromatin Silencing Organelle Organization Chromatin Modification DNA Replication-dependent Nucleosome Assembly Gene Silencing Histone Modification DNA Methylation On Cytosine Nucleosome Assembly Chromatin Assembly Chromatin Silencing At RDNA Nucleosome Organization Chromatin Assembly Or Disassembly Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein-DNA Complex Assembly Negative Regulation Of Cellular Metabolic Process DNA Packaging Negative Regulation Of Gene Expression Cellular Macromolecular Complex Assembly Negative Regulation Of Biosynthetic Process Histone H3-K9 Modification DNA Conformation Change DNA Methylation Protein Complex Assembly DNA Modification Gene Expression Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation N-terminal Peptidyl-lysine Acetylation Histone H4-K20 Demethylation Notch Signaling Pathway Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Megakaryocyte Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process See more
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